Protein Alignment HOXD12 and Ubx

DIOPT Version :10

• Sequence 1: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 71/261 - (27%)
• Similarity: 107/261 - (40%)
• Gaps: 58/261 - (22%)

Human    32 NGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEE 96
            |||..|.....:.|.|.:|  ..|::|.|....|.         ||..||.   .|.:.:.|
  Fly   134 NGGNAANANGQNNPAGGMP--VRPSACTPDSRVGG---------YLDTSGG---SPVSHRGG--- 181

Human    97 QAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALK-AAKYDYAGVGRATPGSTTLLQGA---- 156
                   .|.......|....:...:|.:..|.|... .|....:|....|..:::|.|.:
  Fly   182 -------SAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTF 239

Human   157 --------PCAPGFKDDTKGPLNLNMTVQAAGVA---------SCLRPSLPDGLPWGAAPGRARK 204
                    .|.   :|.||..:..::| |..|::         |.....|||   |....|..|:
  Fly   240 YPWMAIAGECP---EDPTKSKIRSDLT-QYGGISTDMGKRYSESLAGSLLPD---WLGTNGLRRR 297

Human   205 KRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVV-----LRE 264
            .|:.||:.|..|||.||..|.::.|::|.|:::.|.|:::|:||||||||||.|:.:     |.|
  Fly   298 GRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNE 362

Human   265 Q 265
            |
  Fly   363 Q 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		2/19 (11%)
		Homeodomain	203..259	CDD:459649	27/55 (49%)
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	27/55 (49%)