Protein Alignment HOXD12 and NK7.1

DIOPT Version :10

• Sequence 1: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 224
• Identity: 56/224 - (25%)
• Similarity: 88/224 - (39%)
• Gaps: 48/224 - (21%)

Human    52 AATPASCAPAQPAGATAFGGFSQPYL---------AGSGPLGLQPPTAKDGPEEQAKFYAPEAAA 107
            |||.|:...|....||......||..         :.:.|:   |.|      :|::.....|.
  Fly   259 AATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPM---PAT------KQSQILGKSAT- 313

Human   108 GPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGST------TLLQGAPCAPGFKDDT 166
                        ..|||..||....|.:.........:..||:      .|:.....:||...:.
  Fly   314 ------------KKESSGKPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNA 366

Human   167 KGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKK-RKPYTKQQIAELENEFLVNEFINRQ 230
            :...|.|.|::          :..|....|:...|.:|| |..:|.:||.|||..|...::::..
  Fly   367 QMQSNANSTLE----------TTEDDSDSGSTDARRKKKARTTFTGRQIFELEKMFENKKYLSAS 421

Human   231 KRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
            :|.|::..|.:::.||||||||||.|.|:
  Fly   422 ERTEMAKLLMVTETQVKIWFQNRRTKWKK 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		1/19 (5%)
		Homeodomain	203..259	CDD:459649	24/56 (43%)
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	24/55 (44%)