Protein Alignment HOXD12 and scro

DIOPT Version :10

• Sequence 1: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 61/267 - (22%)
• Similarity: 106/267 - (39%)
• Gaps: 77/267 - (28%)

Human    14 SLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLA 78
            |:.::.||....:..|..||.     ||       .|:.:..:|.:...| |.......:.||..
  Fly   117 SVTDILSPIEESYRKLELNGN-----PP-------SPFRSNSSSSSINSP-GTLTTSTMANPYAM 168

Human    79 GSGPLGLQPPTAKDGPEEQAKFYAP--EAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAG 141
            |:                  .:::|  :...||.:          ..|||.....::.:...|
  Fly   169 GT------------------LYHSPGVQTYCGPTD----------NLSLAGHYTDMRNSASWY-- 203

Human   142 VGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQA----------AGVASCLRPSLPDGLPWG 196
                  |||.            :|.:..::..|:..|          :|:|:|   |:.|..|..
  Fly   204 ------GSTA------------NDPRFAISRLMSSSASGTMSHMGNMSGLAAC---SVSDSKPLQ 247

Human   197 AAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVV 261
            ....:.||:|..:|:.|:.|||..|....:::..:|:.|::.::|:..||||||||.|.|.||..
  Fly   248 FPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQA 312

Human   262 LREQALA 268
             :|:|:|
  Fly   313 -KEKAMA 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		3/21 (14%)
		Homeodomain	203..259	CDD:459649	22/55 (40%)
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	22/55 (40%)