Protein Alignment HOXD12 and vnd

DIOPT Version :10

• Sequence 1: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 55/207 - (26%)
• Similarity: 87/207 - (42%)
• Gaps: 47/207 - (22%)

Human    96 EQAKFYAPEAAAGPEERGRTRPSFAPES--------SLAPAVAA-----LKAAKYDYAGVGRA-- 145
            ::.:.|..:..|.|:.   |.|..:..|        ..:||::.     .::|..|...||.|
  Fly   400 KENELYGTQQPASPDS---TSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALH 461

Human   146 ----TPGSTTLLQGAPCAPGFKDDTKGPL-NLNMTVQAAGV---ASCLRPSL------------- 189
                :.|:.: ..|||.|....::..... |.|.:::|.|:   .|....||
  Fly   462 TLHGSSGNGS-AGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVD 525

Human   190 -PDGLPWGAA------PGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVK 247
             .||...|.|      |.:.||:|..:||.|..|||..|....:::..:|:.|::.:.|:..|||
  Fly   526 DADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVK 590

Human   248 IWFQNRRMKKKR 259
            |||||.|.|.||
  Fly   591 IWFQNHRYKTKR 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		4/19 (21%)
		Homeodomain	203..259	CDD:459649	23/55 (42%)
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	23/55 (42%)