Protein Alignment HOXD12 and ind

DIOPT Version :10

• Sequence 1: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 82/291 - (28%)
• Similarity: 117/291 - (40%)
• Gaps: 64/291 - (21%)

Human    23 SFYFSNL---RPNGGQLAALPPISYPRGALPWAATPASCA-----PAQPAGATAFGGFSQPYLAG 79
            ||...:|   |||..|  ....:..|.|:...||..|:.|     |..|..|:..|.    ||..
  Fly     4 SFLMDSLLSDRPNLSQ--KKEKLGSPGGSPTAAAAVAAAAMLPSIPMLPYPASYVGS----YLFS 62

Human    80 SGPLGLQPPTAKDGPEEQ-AKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVG 143
               ||:|....:...::| |...|..|||....:.....|.:|.|...| .|.|.|:|...:|..
  Fly    63 ---LGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHP-YAQLFASKRKSSGFS 123

Human   144 R-----------ATPGSTTL-----LQGAPCAPGFKDDTKGPLNLNMTVQAAG------------ 180
            .           |.|.|..|     |.|:|...|......|....:.:..::.
  Fly   124 NYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQ 188

Human   181 ------VASCLRPSLP-----DGLPWGAAP------GRARKKRKPYTKQQIAELENEFLVNEFIN 228
                  .:||...|.|     .|.|....|      ..:::.|..:|..|:.|||.||..|.:::
  Fly   189 GKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLS 253

Human   229 RQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259
            |.:|.|::|||.||::||||||||||:|:|:
  Fly   254 RLRRIEIANRLRLSEKQVKIWFQNRRVKQKK 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		5/19 (26%)
		Homeodomain	203..259	CDD:459649	28/55 (51%)
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	28/55 (51%)