DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRNA-cap and dusp11

DIOPT Version :9

Sequence 1:	NP_572952.1	Gene:	mRNA-cap / 32379	FlyBaseID:	FBgn0030556	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_001315299.1	Gene:	dusp11 / 550417	ZFINID:	ZDB-GENE-050417-226	Length:	328	Species:	Danio rerio

Alignment Length:	189	Identity:	61/189 - (32%)
Similarity:	95/189 - (50%)	Gaps:	8/189 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LPNRWLYCPRKSDTIIAERFLAFKTPLSNNFHDKMPIECTFQPEMLFEYCKTLKVKLGLWVDLTN 79
            :|:||.........|...||:|||.||..:|...:.....|.|..|....:..:.:|||.:|||.
Zfish     9 VPDRWTDYTSLGKRIPGTRFIAFKVPLKQSFRRHLSESEVFGPFDLVRLLEKERQQLGLIIDLTF 73

  Fly    80 TKRFYDRSAVEEL--GAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFD--VIAVHCTHGF 140
            |.|:|   ..|:|  ...|:|:...|| |.|:.....||.:.|.:|:::...:  :|.||||||.
Zfish    74 TTRYY---RAEDLPDTLYYMKIFTAGH-EVPNDATILSFKKAVRHFLHDNASNDKLIGVHCTHGL 134

  Fly   141 NRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINELYKRYEDTNAAPAAPEQ 199
            ||||:||..||::........|:.:|..:|...|.:|:|:.:|....:.:|.....|:|
Zfish   135 NRTGYLICRYLIDVDGMMPQKAINLFNESRGHSIERQNYLQDLTTGPKRSNNGMDEPDQ 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRNA-cap	NP_572952.1	PTPc	<116..171	CDD:304379	20/56 (36%)
		mRNA_cap_enzyme	307..497	CDD:279649
		mRNA_cap_C	502..597	CDD:281856
dusp11	NP_001315299.1	PTPc	49..174	CDD:304379	44/128 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5226
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1544021at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820