DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRNA-cap and CG13197

DIOPT Version :9

Sequence 1:	NP_572952.1	Gene:	mRNA-cap / 32379	FlyBaseID:	FBgn0030556	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_001286319.1	Gene:	CG13197 / 36253	FlyBaseID:	FBgn0062449	Length:	343	Species:	Drosophila melanogaster

Alignment Length:	334	Identity:	91/334 - (27%)
Similarity:	144/334 - (43%)	Gaps:	53/334 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LPNRWLYCPRKSDTIIAERFLAFKTPLSNNFHDKMPIECTFQPEMLFEYCKTLKVKLGLWVDLTN 79
            :|:|||......|.:...||:|||.||:.:.:.|:.......||.|.:    :...:||.:||||
  Fly     5 IPDRWLKYKPIGDRVPGTRFIAFKVPLNQHVNAKVKENLRLAPESLLQ----IVPDMGLIIDLTN 65

  Fly    80 TKRFYDRSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFD---VIAVHCTHGFN 141
            |.|:|..||:......:.||...|. :|||.:....|...|.:|: ||..|   :|.||||||.|
  Fly    66 TNRYYHPSAITNHDVLHQKLMIPGK-QTPSHKLAQRFCAFVTDFL-ERNADNDKLIGVHCTHGVN 128

  Fly   142 RTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINELYK-RYEDTNAAPAAPEQ-----P 200
            |||:||..:::..::.|...|:..|:.||...|.:.:|::.|.. ...:|....||.|:     .
  Fly   129 RTGYLICYFMISVMNMSPEEAIQTFSLARGHEIERDNYLSSLKTLPNRETVTKLAATERRSSTID 193

  Fly   201 NWCLDYDDGNGDGFVQDNS---SSTSQQAGEQDDDAEEVEGEDAGGDCDASTSDGQPRKKRRREM 262
            ||....|..:.....|.|:   |...:....|:.|           ||            |||:.
  Fly   194 NWRQPIDYQSERDLHQKNNHRLSKVLKTKSYQEHD-----------DC------------RRRDR 235

  Fly   263 IIKNATFMAGVPGVRQVSDQPRLGDLQRKVQDWCDWKKNGF-PGAQPVSMDRENIKRLSEIPYRV 326
            ..::       |..|  :.:|...:.||::|.  :..::|: .|:......|.:.....|..||:
  Fly   236 WNQH-------PYAR--NHRPHPVEEQRRIQS--NRSRDGYQQGSNQHPYSRNHRPHPVEEQYRI 289

  Fly   327 SWKADGTRY 335
            .....|..|
  Fly   290 QSNRSGGGY 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRNA-cap	NP_572952.1	PTPc	<116..171	CDD:304379	23/57 (40%)
		mRNA_cap_enzyme	307..497	CDD:279649	6/29 (21%)
		mRNA_cap_C	502..597	CDD:281856
CG13197	NP_001286319.1	PTPc	43..171	CDD:304379	46/133 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5226
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1544021at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10367
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850