Protein Alignment mRNA-cap and cel-1

DIOPT Version :9

• Sequence 1: NP_572952.1
• Gene: mRNA-cap / 32379
• FlyBaseID: FBgn0030556
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001020979.1
• Gene: cel-1 / 172814
• WormBaseID: WBGene00000466
• Length: 623
• Species: Caenorhabditis elegans
• Alignment Length: 666
• Identity: 259/666 - (38%)
• Similarity: 359/666 - (53%)
• Gaps: 87/666 - (13%)

  Fly    10 RGSGP------LPNRWLYCPRKSDTIIAERFLAFKTPLSNNFHDKMPIECTFQ--PEMLFEYCKT 66
            ||..|      ||:|||:|| |:.|:|...|..|||||. ..:|....|..:|  |..:|.:...
 Worm     4 RGPTPDKARMGLPDRWLHCP-KTGTLINNLFFPFKTPLC-KMYDNQIAERRYQFHPAEVFSHPHL 66

  Fly    67 LKVKLGLWVDLTNTKRFYDRSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDV 131
            ...|:|||:|||||.|:|.|..|.|....|.|::..|.|.:|:.|.|.:||::|..|..:.|..|
 Worm    67 HGKKIGLWIDLTNTDRYYFREEVTEHECIYHKMKMAGRGVSPTQEDTDNFIKLVQEFHKKYPDRV 131

  Fly   132 IAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINELYKRYEDT-NAAPA 195
            :.||||||||||||||..||.:..:..:.||:..||..|..||||||||::|:.||:.| :....
 Worm   132 VGVHCTHGFNRTGFLIAAYLFQVEEYGLDAAIGEFAENRQKGIYKQDYIDDLFARYDPTEDDKIL 196

  Fly   196 APEQPNWCLDYDDGNGDGFVQDNSSSTSQQA----GEQDDDAEEVEGEDAGGDCDASTSDGQPRK 256
            |||:|:|..:...|.... :.:...|||||.    |..:.:..::.|   |||
 Worm   197 APEKPDWEREMSIGMSTQ-IDNGRPSTSQQIPATNGNNNQNGNQLSG---GGD------------ 245

  Fly   257 KRRREMIIKNATFMAG-VPGVRQVSDQPRLGDLQRKVQDWCDWKKNGFPGAQPVSMDRENIKRLS 320
                    .:..||.| :.||:...|:.:...||.|:::.|.:.|.||||.||||:.|.||..|.
 Worm   246 --------NSKLFMDGLIRGVKVCEDEGKKSMLQAKIKNLCKYNKQGFPGLQPVSLSRGNINLLE 302

  Fly   321 EIPYRVSWKADGTRYMMLIDGRDEVYFFDRNHSCFQVENVTFVESRNLNEHLDGTLVDGEMVLDK 385
            :..|.|||||||.||::.|:..| ||.|||::..|::||:.|| ::| ...|..||||.|:::||
 Worm   303 QESYMVSWKADGMRYIIYINDGD-VYAFDRDNEVFEIENLDFV-TKN-GAPLMETLVDTEVIIDK 364

  Fly   386 I----GETVTPRYLIYDIVRLSNRDVRDEPFYPNRLDYIKTEVIGPRILGMKHGIINQRLQAFSV 446
            :    .....||.|||||:|.::.:|..|||| .|.:.||||:|..|....|.|.:....|..||
 Worm   365 VEINGAMCDQPRMLIYDIMRFNSVNVMKEPFY-KRFEIIKTEIIDMRTAAFKTGRLKHENQIMSV 428

  Fly   447 RGKDFWDIWMSARLLGEKFSRTLAHEPDGLIFQPSKQPYTAGTCSDVFKWKPHELNSVDFRLKII 511
            |.|||:|:..:|:|.|.||.:.:.||.|||||||.|..|..|.|..|.||||...|||||.||:.
 Worm   429 RRKDFYDLEATAKLFGPKFVQHVGHEIDGLIFQPKKTKYETGRCDKVLKWKPPSHNSVDFLLKVE 493

  Fly   512 TERGEGLLTKKVGFLYVGGHDAPYGRMQRLTKETRELDNRIVECTM---NQFG---NWDFMRERT 570
            .:..||:|.:.:|:|:|.....|:|.| :.|...::..|:|:|||:   || |   .|.||||||
 Worm   494 KKCKEGMLPEWIGYLFVQNLSDPFGTM-KATATLKKYHNKIIECTLLVDNQ-GRPKEWKFMRERT 556

  Fly   571 DKKNPNSYNTARSVVDSIKHPVTKEYLLNFIASSGYRNDHVMMPPPINSHNQNH----------N 625
            ||..||...||.:||:::.:|||:.||:.::                     ||          .
 Worm   557 DKSLPNGLRTAENVVETMVNPVTETYLIEYV---------------------NHALRVLKRAAAA 600

  Fly   626 HNHFYPHGHGQHQRRP 641
            |.|...|....|:..|
 Worm   601 HRHHQIHQQQLHEGEP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRNA-cap	NP_572952.1	PTPc	<116..171	CDD:304379	26/54 (48%)
		mRNA_cap_enzyme	307..497	CDD:279649	89/193 (46%)
		mRNA_cap_C	502..597	CDD:281856	43/100 (43%)
cel-1	NP_001020979.1	PTPc	<115..171	CDD:304379	26/55 (47%)
		mRNA_cap_enzyme	289..479	CDD:279649	89/193 (46%)
		mRNA_cap_C	484..583	CDD:281856	43/100 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156498
Domainoid	1	1.000	160	1.000	Domainoid score	I2483
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37851
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1030
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57294
OrthoDB	1	1.010	-	-		D1544021at2759
OrthoFinder	1	1.000	-	-		FOG0003817
OrthoInspector	1	1.000	-	-		oto20453
orthoMCL	1	0.900	-	-		OOG6_101990
Panther	1	1.100	-	-	LDO	PTHR10367
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R688
SonicParanoid	1	1.000	-	-		X2661
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940