Protein Alignment mRNA-cap and mRNA-cap

DIOPT Version :10

• Sequence 1: NP_572952.1
• Gene: mRNA-cap / 32379
• FlyBaseID: FBgn0030556
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_314026.5
• Gene: mRNA-cap / 1274820
• VectorBaseID: AGAMI1_007049
• Length: 606
• Species: Anopheles gambiae
• Alignment Length: 618
• Identity: 334/618 - (54%)
• Similarity: 426/618 - (68%)
• Gaps: 28/618 - (4%)

  Fly    10 RGSGPLPNRWLYCPRKSDTIIAERFLAFKTPLSNNFHDKMPIECTFQPEMLFEYCKTLKVKLGLW 74
            ||.||:|:|||:||||||:|||:||:||||||..:|..:||::|:|.|.|||:..|..|.::|||
Mosquito     3 RGPGPIPHRWLHCPRKSDSIIADRFIAFKTPLKRDFQSQMPVQCSFAPSMLFDLMKRQKRRIGLW 67

  Fly    75 VDLTNTKRFYDRSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDVIAVHCTHG 139
            :|||||.||||::.:|:.||.||||:|||||||||.|...||||||:.||.|.|.|||.||||||
Mosquito    68 IDLTNTNRFYDKNEIEDAGATYIKLKCRGHGETPSVEHVRSFIEIVEEFIQEHPLDVIGVHCTHG 132

  Fly   140 FNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINELYKRYEDTNAAPAAPEQPNWCL 204
            |||||||||.|:||||||:|.||:..||.||||||||.||:.||:.||.|...||..||.|.|||
Mosquito   133 FNRTGFLIVSYMVERLDCAVDAAVMAFAQARPPGIYKGDYLKELFARYGDVEDAPPPPELPAWCL 197

  Fly   205 DYDDGNGDGFVQDNSSSTSQQAGEQDDDAEEVEGEDAGGDCD-------ASTSDGQPR--KKRRR 260
            :||||       |..::.:.|..|||||      :|.||:..       :...:|.|:  |:.:|
Mosquito   198 EYDDG-------DQPNNGAHQLVEQDDD------DDGGGEESRPRGSKRSQEGEGAPQTPKRFKR 249

  Fly   261 EMIIKNATFMAGVPGVRQVSDQPRLGDLQRKVQDWCDWKKNGFPGAQPVSMDRENIKRLSEIPYR 325
            .....||.||..||||..|.|:..:..||.:|::.|..|..||.||||||||..||:.|.|:|||
Mosquito   250 ASYNPNAVFMEDVPGVTLVRDEALIAKLQERVREMCGSKLQGFAGAQPVSMDMHNIRYLKEMPYR 314

  Fly   326 VSWKADGTRYMMLIDGRDEVYFFDRNHSCFQVENVTFVESRNLNEHLDGTLVDGEMVLDKIGE-T 389
            ||||||||||||||....|:||.||::|.|:.|.:.|...::.:.|:..||||||||||..|| .
Mosquito   315 VSWKADGTRYMMLIHREGEIYFLDRDNSVFKAEGIRFPTLKDTSVHITDTLVDGEMVLDNYGEGK 379

  Fly   390 VTPRYLIYDIVRLSNRDVRDEPFYPNRLDYIKTEVIGPRILGMKHGIINQRLQAFSVRGKDFWDI 454
            ..||||:||::.|.||:||.:.|:|:||..|..|:|.||...::.|.:::..:.|.||.|.||||
Mosquito   380 KIPRYLVYDVIYLHNREVRKQRFFPDRLGLIDREIIQPRTNAIRQGRLDRESEPFGVRLKQFWDI 444

  Fly   455 WMSARLLGEKFSRTLAHEPDGLIFQPSKQPYTAGTCSDVFKWKPHELNSVDFRLKIITERGEGLL 519
            ..|..|||.||::.|.|||||||||||..||.:|.|..|.|||||.:||:||||.|..|.|:|:|
Mosquito   445 MQSRALLGPKFTKGLGHEPDGLIFQPSIDPYESGVCPRVLKWKPHHMNSIDFRLVIKEETGQGML 509

  Fly   520 TKKVGFLYVGGHDAPYGRMQRLTKETRELDNRIVECTMNQFGN-WDFMRERTDKKNPNSYNTARS 583
            ..|.|.|||||.:..||.: :||||.|:|:|:|:||   :|.| |..|||||||..||||.||::
Mosquito   510 PTKKGLLYVGGMEHSYGEI-KLTKELRKLNNKIIEC---KFENGWVLMRERTDKSFPNSYETAKN 570

  Fly   584 VVDSIKHPVTKEYLLNFIASSGYRNDHVMMPPP 616
            |.:||::|||::.||..||..|:|:|..:||||
Mosquito   571 VWESIRNPVTEDRLLTLIAKDGFRSDAELMPPP 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRNA-cap	NP_572952.1	Mce1_N	18..185	CDD:350502	112/166 (67%)
		mRNA_cap_enzyme	307..497	CDD:396068	102/190 (54%)
		mRNA_cap_C	502..597	CDD:461093	52/95 (55%)
mRNA-cap	XP_314026.5	None