DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and AMN1

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_009716.1 Gene:AMN1 / 852455 SGDID:S000000362 Length:549 Species:Saccharomyces cerevisiae


Alignment Length:383 Identity:80/383 - (20%)
Similarity:142/383 - (37%) Gaps:85/383 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   321 APQICLTDL----PFEILLRILSYLDLKSLFRVGHVSRTFYD--ISRHPLLYAEISLKPYWDVAS 379
            :|....|.|    ||:.::|...          ||:.::.|:  .|:..|:..::|||.......
Yeast    33 SPSPSFTSLKMEKPFKDIVRKYG----------GHLHQSSYNPGSSKVELVRPDLSLKTDQSFLQ 87

  Fly   380 SELLCTLARR----------ATMLRK--LDLSW-------CGGFGNVSPTEFKKFLTQRGDNLTH 425
            |.:..|..::          ||.|:.  .:.:|       ......|:|||.|..|.   |..:.
Yeast    88 SSVQTTPNKKSCNEYLSTPEATPLKNTATENAWATSRVVSASSLSIVTPTEIKNILV---DEFSE 149

  Fly   426 LRLN---SCKFLNASCIENVGIVCDNLIELSL----------RNCATEPPLLNFSCLANLKNLER 477
            |:|.   :.:...:..:..:..:.:|:|::.:          |.|....|......|...|:.||
Yeast   150 LKLGQPLTAQHQRSHAVFEIPEIVENIIKMIVSLESANIPKERPCLRRNPQSYEHSLLMYKDEER 214

  Fly   478 L----DLFQTYFETEL----------LLSMLEGNRKLKHLNLAFCGVSV---NMDNVAAHLAT-- 523
            .    ...|...:..|          |.|.:..||...::...|...|:   ::.|....|.|  
Yeast   215 AKKAWSAAQQLRDPPLVGHKEKKQGALFSCMMVNRLWLNVTRPFLFKSLHFKSVHNFKEFLRTSQ 279

  Fly   524 YNTQLISLDLWKAHFLSSRGLQSLARLHQLEELDLGW-----CMREASLGDGLFQLLS---NCPK 580
            ..||::....:..|.|.......:.||.::|..:|.|     |.|       :...||   |..|
Yeast   280 ETTQVMRPSHFILHKLHQVTQPDIERLSRMECQNLKWLEFYVCPR-------ITPPLSWFDNLHK 337

  Fly   581 LKKLFLSAVRGTTERDLMHIAALGKNLEQLDLMGILNITHERVYDILVNCPKLQLLDL 638
            |:||.:...:...:..|:.::....||:.|.|....|::...|..|.:|||||:..::
Yeast   338 LEKLIIPGNKNIDDNFLLRLSQSIPNLKHLVLRACDNVSDSGVVCIALNCPKLKTFNI 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 11/51 (22%)
leucine-rich repeat 393..422 CDD:275381 8/37 (22%)
leucine-rich repeat 423..442 CDD:275381 2/21 (10%)
LRR_RI 437..>641 CDD:238064 51/239 (21%)
leucine-rich repeat 449..474 CDD:275381 5/34 (15%)
leucine-rich repeat 475..499 CDD:275381 7/37 (19%)
leucine-rich repeat 500..527 CDD:275381 5/31 (16%)
leucine-rich repeat 528..552 CDD:275381 4/23 (17%)
AMN1 552..>660 CDD:187754 25/95 (26%)
leucine-rich repeat 553..580 CDD:275381 8/34 (24%)
leucine-rich repeat 581..606 CDD:275381 4/24 (17%)
leucine-rich repeat 607..632 CDD:275381 8/24 (33%)
leucine-rich repeat 633..652 CDD:275381 1/6 (17%)
AMN1NP_009716.1 AMN1 285..509 CDD:187754 29/118 (25%)
leucine-rich repeat 314..337 CDD:275381 7/29 (24%)
leucine-rich repeat 338..363 CDD:275381 4/24 (17%)
leucine-rich repeat 364..389 CDD:275381 8/24 (33%)
leucine-rich repeat 390..417 CDD:275381 1/6 (17%)
leucine-rich repeat 418..443 CDD:275381
leucine-rich repeat 444..471 CDD:275381
leucine-rich repeat 472..493 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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