DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fbxl4 and AT1G55590

DIOPT Version :9

Sequence 1:	NP_572951.1	Gene:	Fbxl4 / 32378	FlyBaseID:	FBgn0030555	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_175955.1	Gene:	AT1G55590 / 842008	AraportID:	AT1G55590	Length:	607	Species:	Arabidopsis thaliana

Alignment Length:	502	Identity:	107/502 - (21%)
Similarity:	172/502 - (34%)	Gaps:	184/502 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 LTKTLRIDFNHSRLNYYTEIDAIMLCGR-TVTKTQNLLAKQQITQ--HSRTLVSPPPDAIGSTSG 270
            |.:||:.    .||....|.:||:|..| .||.|       .::|  ::..|:||.|
plant   172 LPETLKA----LRLQPLLESEAILLMNRFKVTGT-------YLSQPDYNSALLSPSP-------- 217

  Fly   271 DGSGGSISHKLRTLKFQPNCGEDGATKLHEFINNDLSQFLADNCVDG-EAAAPQICLTDL----- 329
                   |..|::|..                   :...::|..:.. ..:.||:...||
plant   218 -------SFTLQSLSL-------------------VLDLISDRLIIAITGSLPQLVKLDLEDRPE 256

  Fly   330 --PFEILLRILSYLDLKSLFRVGHVS-----RTFYDISRHPLLYAEISLKPYWDVASSELLCTLA 387
              ||..  ..|:|..|::|.....::     ||.|:        .:||.|...|:.    :..|:
plant   257 KEPFPD--NDLTYTGLQALGFCQQLTSLSLVRTCYN--------RKISFKRINDMG----IFLLS 307

  Fly   388 RRATMLRKLDLSWCGGFGNVSPTEF----------KKF---------------LTQRGDNLTHLR 427
            .....|..:.|   |||..||...|          |||               :|....:|..:|
plant   308 EACKGLESVRL---GGFPKVSDAGFASLLHSCRNLKKFEVRGAFLLSDLAFHDVTGSSCSLQEVR 369

  Fly   428 LNSCKFLNASCIENVGIVCDNLIELSLRNCATEPPLLNFSCLANLKNLERLDLFQTYFETELLLS 492
            |::|..:.:..::.:|: |.||..|.|.:|.:    ::.|||.::..|
plant   370 LSTCPLITSEAVKKLGL-CGNLEVLDLGSCKS----ISDSCLNSVSAL----------------- 412

  Fly   493 MLEGNRKLKHLNLAFCGVSVNMDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLARLH-QLEEL 556
                 |||..||||  |..|                           :..|:.:|.:.. .:.:|
plant   413 -----RKLTSLNLA--GADV---------------------------TDSGMLALGKSDVPITQL 443

  Fly   557 DLGWCMREASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHIAALGKNLEQLDLMGILNITHE 621
            .|..|.|.:.  .|:..||:|            .||          :.|.|..|||..:..|:..
plant   444 SLRGCRRVSD--RGISYLLNN------------EGT----------ISKTLSTLDLGHMPGISDR 484

  Fly   622 RVYDILVNCPKLQLLDLSFCDNIMDRDFDLLAEWSRQFKVDIKSSRR 668
            .::.|...|..|..|.:..|.::.|...:.||.|.||.:...|..|:
plant   485 AIHTITHCCKALTELSIRSCFHVTDSSIESLATWERQAEGGSKQLRK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl4	NP_572951.1	F-box-like	326..372	CDD:289689	13/57 (23%)
		leucine-rich repeat	393..422	CDD:275381	12/53 (23%)
		leucine-rich repeat	423..442	CDD:275381	4/18 (22%)
		LRR_RI	437..>641	CDD:238064	42/204 (21%)
		leucine-rich repeat	449..474	CDD:275381	7/24 (29%)
		leucine-rich repeat	475..499	CDD:275381	1/23 (4%)
		leucine-rich repeat	500..527	CDD:275381	7/26 (27%)
		leucine-rich repeat	528..552	CDD:275381	2/24 (8%)
		AMN1	552..>660	CDD:187754	27/107 (25%)
		leucine-rich repeat	553..580	CDD:275381	8/26 (31%)
		leucine-rich repeat	581..606	CDD:275381	2/24 (8%)
		leucine-rich repeat	607..632	CDD:275381	7/24 (29%)
		leucine-rich repeat	633..652	CDD:275381	4/18 (22%)
AT1G55590	NP_175955.1	leucine-rich repeat	14..43	CDD:275381
		leucine-rich repeat	44..68	CDD:275381
		leucine-rich repeat	69..85	CDD:275381
		leucine-rich repeat	92..117	CDD:275381
		leucine-rich repeat	118..147	CDD:275381
		leucine-rich repeat	148..174	CDD:275381	1/1 (100%)
		leucine-rich repeat	176..218	CDD:275381	16/67 (24%)
		leucine-rich repeat	221..245	CDD:275381	3/42 (7%)
		leucine-rich repeat	246..274	CDD:275381	7/29 (24%)
		leucine-rich repeat	279..300	CDD:275381	6/28 (21%)
		leucine-rich repeat	313..338	CDD:275381	8/27 (30%)
		leucine-rich repeat	339..364	CDD:275381	4/24 (17%)
		leucine-rich repeat	365..389	CDD:275381	6/24 (25%)
		AMN1	386..559	CDD:187754	50/226 (22%)
		leucine-rich repeat	390..414	CDD:275381	8/49 (16%)
		leucine-rich repeat	415..439	CDD:275381	9/52 (17%)
		leucine-rich repeat	440..469	CDD:275381	10/52 (19%)
		leucine-rich repeat	470..495	CDD:275381	7/24 (29%)
		leucine-rich repeat	496..515	CDD:275381	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900