DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and SKIP2

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_569047.1 Gene:SKIP2 / 836860 AraportID:AT5G67250 Length:527 Species:Arabidopsis thaliana


Alignment Length:382 Identity:90/382 - (23%)
Similarity:150/382 - (39%) Gaps:70/382 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   313 NCVDGEAAAPQICLTDLPFEILLRILSYLDLKSLFRVGHVSRTFYDI---SRHPLLYAEISLKPY 374
            |.||.:...      |||.|.|..:..:|......|...|.:.:..:   |||     .:||...
plant    36 NVVDRDFTG------DLPDECLAHVFQFLGAGDRKRCSLVCKRWLLVDGQSRH-----RLSLDAK 89

  Fly   375 WDVASSELLCTLARRATMLRKLDLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCI 439
            .:::|  .|.::..|...:.||.|. |.........|....::.|..|||.::|..|:.:....:
plant    90 DEISS--FLTSMFNRFDSVTKLALR-CDRKSVSLSDEALAMISVRCLNLTRVKLRGCREITDLGM 151

  Fly   440 ENVGIVCDNLIELSLRNCATEPPLLNF------SCLANLKNLERL-------------------D 479
            |:....|.||.:||:.:|       ||      :.|.:.|.||.|                   |
plant   152 EDFAKNCKNLKKLSVGSC-------NFGAKGVNAMLEHCKLLEELSVKRLRGIHEAAELIHLPDD 209

  Fly   480 LFQTYFETELLLSMLEG---------NRKLKHLNLAFC-GVSVNMDNVAAHLATYNTQLISLDLW 534
            ...:...:..|..::.|         .|.||.|.:..| |   :.|.|...:|...:.|..:.|.
plant   210 ASSSSLRSICLKELVNGQVFEPLLATTRTLKTLKIIRCLG---DWDKVLQMIANGKSSLSEIHLE 271

  Fly   535 KAHFLSSRGLQSLARLHQLEELDLGWCMREASLGD-GLFQLLSNCPKLKKLFLSAVRGTT--ERD 596
            :.. :|..||.::::...:|.|.:   ::.....: ||..:...|..|:||.:...|...  :..
plant   272 RLQ-VSDIGLSAISKCSNVETLHI---VKTPECSNFGLIYVAERCKLLRKLHIDGWRTNRIGDEG 332

  Fly   597 LMHIAALGKNLEQLDLMGILNITHERVYDILVNCPKLQLLDLSFCDNIMDRDFDLLA 653
            |:.:|....||::|.|:|: |.||..:..|..||.||:.|.|.....|.|.:...:|
plant   333 LLSVAKHCLNLQELVLIGV-NATHMSLAAIASNCEKLERLALCGSGTIGDTEIACIA 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 12/48 (25%)
leucine-rich repeat 393..422 CDD:275381 6/28 (21%)
leucine-rich repeat 423..442 CDD:275381 5/18 (28%)
LRR_RI 437..>641 CDD:238064 57/241 (24%)
leucine-rich repeat 449..474 CDD:275381 7/30 (23%)
leucine-rich repeat 475..499 CDD:275381 6/51 (12%)
leucine-rich repeat 500..527 CDD:275381 8/27 (30%)
leucine-rich repeat 528..552 CDD:275381 5/23 (22%)
AMN1 552..>660 CDD:187754 29/105 (28%)
leucine-rich repeat 553..580 CDD:275381 5/27 (19%)
leucine-rich repeat 581..606 CDD:275381 6/26 (23%)
leucine-rich repeat 607..632 CDD:275381 10/24 (42%)
leucine-rich repeat 633..652 CDD:275381 5/18 (28%)
SKIP2NP_569047.1 F-box-like 45..>73 CDD:403981 8/27 (30%)
AMN1 82..295 CDD:187754 50/234 (21%)
leucine-rich repeat 106..128 CDD:275381 5/22 (23%)
leucine-rich repeat 135..160 CDD:275381 6/24 (25%)
leucine-rich repeat 161..185 CDD:275381 7/30 (23%)
leucine-rich repeat 239..264 CDD:275381 8/27 (30%)
leucine-rich repeat 265..288 CDD:275381 5/23 (22%)
leucine-rich repeat 289..314 CDD:275381 5/27 (19%)
AMN1 <311..>416 CDD:187754 25/79 (32%)
leucine-rich repeat 315..342 CDD:275381 6/26 (23%)
leucine-rich repeat 343..367 CDD:275381 10/24 (42%)
leucine-rich repeat 368..393 CDD:275381 6/21 (29%)
leucine-rich repeat 394..418 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 50 1.000 Domainoid score I4364
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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