DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and fbxl17

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_001335097.5 Gene:fbxl17 / 795023 ZFINID:ZDB-GENE-111013-3 Length:409 Species:Danio rerio


Alignment Length:381 Identity:74/381 - (19%)
Similarity:123/381 - (32%) Gaps:113/381 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 YTEIDAIMLCGRTVTKTQNLLAKQQITQHSRTLVSPPPDAIGSTSGDGSGGSISHKLRTLKFQPN 289
            |:|    |:|.|.....|....::|     .....|.|...|...||.:.......|.::...|:
Zfish   111 YSE----MVCKRKCADLQRCSPRKQ-----PRCAFPGPMENGEERGDAAAPDSHCLLPSICPLPS 166

  Fly   290 CG---------EDGATKLHEFINNDLSQFLADNCVDGEAAAPQICLTD---------LPFEILLR 336
            ..         |||||..........:...:.:|.....|:.:|..|:         ||..|||:
Zfish   167 SSSSSSSSASEEDGATAGRHSDPGGATTCSSSSCCCQTEASEEIKSTENTDTSHINQLPSSILLK 231

  Fly   337 ILSYLDLKSLFRVGHVSRTFYDISRHPLLYAEISLKPYWDVASSELLCTLARRATMLRKLDLSWC 401
            :.|:|.:|                 ...|.|.:..| ||.        .|.......:::|||  
Zfish   232 VFSHLSVK-----------------ERCLAASLVCK-YWR--------DLCLDFQFWKQIDLS-- 268

  Fly   402 GGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVCDNLIELSLRNCATEPPLLNF 466
             |...|......|..::| .|:|.:.::.|:.:....:..:...|..||:.:...|         
Zfish   269 -GLQQVKDDLLVKIASRR-QNVTEINISDCRNVQDHGVCALASNCAGLIKYTAYRC--------- 322

  Fly   467 SCLANLKNLERLDLFQTYFETELLLSMLEGNRKLKHLNLAFCGVSVNMDNVAAHLATYNTQLISL 531
                  |.|..:.|........||..:..||:                |.:..|         :|
Zfish   323 ------KQLSDVSLSTVAIHCPLLQKVHVGNQ----------------DKLTDH---------AL 356

  Fly   532 DLWKAHFLSSRGLQSLARLHQLEELDLGWCMREASLGD-GLFQLLSNCPKLKKLFL 586
            .|...|            ..:|:::..|.|.   |:.| ||..|...|.||:::::
Zfish   357 KLLGDH------------CKELKDVHFGQCY---SISDEGLMSLAQGCNKLQRIYM 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 11/54 (20%)
leucine-rich repeat 393..422 CDD:275381 7/28 (25%)
leucine-rich repeat 423..442 CDD:275381 2/18 (11%)
LRR_RI 437..>641 CDD:238064 27/151 (18%)
leucine-rich repeat 449..474 CDD:275381 3/24 (13%)
leucine-rich repeat 475..499 CDD:275381 6/23 (26%)
leucine-rich repeat 500..527 CDD:275381 2/26 (8%)
leucine-rich repeat 528..552 CDD:275381 3/23 (13%)
AMN1 552..>660 CDD:187754 11/36 (31%)
leucine-rich repeat 553..580 CDD:275381 9/27 (33%)
leucine-rich repeat 581..606 CDD:275381 1/6 (17%)
leucine-rich repeat 607..632 CDD:275381
leucine-rich repeat 633..652 CDD:275381
fbxl17XP_001335097.5 F-box-like 221..268 CDD:289689 15/72 (21%)
AMN1 257..>397 CDD:187754 37/198 (19%)
leucine-rich repeat 262..287 CDD:275381 7/28 (25%)
leucine-rich repeat 288..313 CDD:275381 3/24 (13%)
leucine-rich repeat 314..339 CDD:275381 6/39 (15%)
leucine-rich repeat 340..365 CDD:275381 8/61 (13%)
leucine-rich repeat 366..391 CDD:275381 9/27 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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