DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and Lrrc29

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_006255593.1 Gene:Lrrc29 / 502201 RGDID:1593150 Length:673 Species:Rattus norvegicus


Alignment Length:682 Identity:155/682 - (22%)
Similarity:239/682 - (35%) Gaps:224/682 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 VPTEV--------AIFETFNPGAVVRIWAYGLTKNWTCLWEATESDLSRPPPLDSRRFAPSLKKT 206
            :|.||        :|.|..:|             .||   .:..||:.||..:.|       |..
  Rat     5 LPLEVYSEAGEGKSILEVLDP-------------RWT---RSQFSDILRPRGIGS-------KAL 46

  Fly   207 TMLTKTLRIDFNHSRLNYYTEI-------DAIMLCGRTVTKTQNLLAKQQITQHSRTLVSPPPDA 264
            .:||....:.|:...|.|....       :|.::........||.|.:..: :::..:.|....|
  Rat    47 RVLTPLKHLIFSPQMLTYILSFLPLSDQKEASLVSRAWYYAAQNALRETNV-RYNIPVSSASLSA 110

  Fly   265 IGSTSGDGSGGSISHKLRTLKFQPNCGEDGATKLHEFINN---DLSQFLADNCVDGEAAAPQICL 326
            |.|.   |..|.....|..|        ||:...|:.:.:   .|...|...|:.|  .:|    
  Rat   111 IKSL---GRRGISCISLTNL--------DGSPASHQVLQSVAYHLGPHLQSLCLGG--GSP---- 158

  Fly   327 TDLPFEILL---RILSYLDL---KSLFRVG----------------------------------- 350
            |:..|..|:   .:|..|||   .|||..|                                   
  Rat   159 TEASFLALILGCPVLRTLDLSGCNSLFTSGTLLAQPETAQCVRKALSGLRDLNLAGLRDLTDLSF 223

  Fly   351 -HVSRTFYDISRHPLLYAEIS--LKPYWDVASSE-----------LLCTLARRATMLRKLDLSWC 401
             |:|..|..:.|..|.|..::  |...|...|.:           ||..:..||..||.||||  
  Rat   224 NHLSSCFPSLERLSLAYCHLTFELGSTWGSTSPQASSPSQLSFHNLLQFIKERAGTLRALDLS-- 286

  Fly   402 GGFGNVSPTEFKKFLTQ-RGDNLTHLRLNSCKFLNASCIENVGIVC---DNLIELSLRNCA--TE 460
               |...|.|..:.|.| .|..|..|.|||||.|::   |.|..:|   ..|..|.|..|:  |:
  Rat   287 ---GTGLPPEALQALGQVTGLKLEELNLNSCKDLSS---EAVATLCRQQPGLTSLDLSGCSELTD 345

  Fly   461 PPLLNFS---------------------CLA--NLKNLERLDLFQTYFETELLLSMLEGNRK--- 499
            ..||..|                     |:|  .|..|:.||:.:....:...|:.:.|:.:   
  Rat   346 RALLAVSRGLHHLRHLSLKKLQRLTDAGCIALGALHELQSLDMAECCLVSGRELAQVLGSVRRAP 410

  Fly   500 --LKHLNLAFC---------------GVSVNMDNVAAHLATYN-------TQLISLDLWKAHF-- 538
              |..|.||:|               |.|:.:.::::.:|..|       |.||.|.:.:..:  
  Rat   411 PALTSLRLAYCSSLKDASVLSMIPALGPSLKVLDLSSCVALTNQTMQAICTYLIHLSVLRLAWCK 475

  Fly   539 -LSSRGLQSL----------ARLHQ--------------------------LEELDLGWC--MRE 564
             |...||..|          .:|||                          |:||||..|  :.:
  Rat   476 ELQDWGLLGLKEPSDEPVLNPQLHQEVENQAPDHQEPSSEPQGSSLLMLQALQELDLTACSKLTD 540

  Fly   565 ASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHIAALGKNLEQLDLMGILNITHERVYDILVN 629
            |||...|     ..|:|::|.||.:...|:..|:.:|....:||:|.|....:::.|........
  Rat   541 ASLAKVL-----QFPQLRQLSLSLLPAFTDMGLVAVARGCPSLERLTLSHCSHLSDEGWVQAARL 600

  Fly   630 CPKLQLLDLSFCDNIMDRDFDLLAEWSRQFKV 661
            .|:||.|:||.|..:.::..|.:.:..:|.:|
  Rat   601 WPRLQHLNLSSCSQVTEQTLDTIGQACKQLRV 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 17/89 (19%)
leucine-rich repeat 393..422 CDD:275381 12/29 (41%)
leucine-rich repeat 423..442 CDD:275381 9/18 (50%)
LRR_RI 437..>641 CDD:238064 68/299 (23%)
leucine-rich repeat 449..474 CDD:275381 11/49 (22%)
leucine-rich repeat 475..499 CDD:275381 5/23 (22%)
leucine-rich repeat 500..527 CDD:275381 9/48 (19%)
leucine-rich repeat 528..552 CDD:275381 8/36 (22%)
AMN1 552..>660 CDD:187754 33/135 (24%)
leucine-rich repeat 553..580 CDD:275381 10/28 (36%)
leucine-rich repeat 581..606 CDD:275381 7/24 (29%)
leucine-rich repeat 607..632 CDD:275381 5/24 (21%)
leucine-rich repeat 633..652 CDD:275381 7/18 (39%)
Lrrc29XP_006255593.1 leucine-rich repeat 124..142 CDD:275381 5/25 (20%)
LRR_RI <170..410 CDD:238064 60/247 (24%)
leucine-rich repeat 173..206 CDD:275381 8/32 (25%)
leucine-rich repeat 207..232 CDD:275381 3/24 (13%)
leucine-rich repeat 233..279 CDD:275381 10/45 (22%)
leucine-rich repeat 280..300 CDD:275381 10/24 (42%)
AMN1 292..480 CDD:187754 45/190 (24%)
leucine-rich repeat 306..331 CDD:275381 11/27 (41%)
leucine-rich repeat 332..357 CDD:275381 8/24 (33%)
leucine-rich repeat 358..439 CDD:275381 14/80 (18%)
leucine-rich repeat 383..408 CDD:275381 5/24 (21%)
leucine-rich repeat 413..437 CDD:275381 5/23 (22%)
leucine-rich repeat 440..465 CDD:275381 4/24 (17%)
leucine-rich repeat 466..526 CDD:275381 8/59 (14%)
leucine-rich repeat 527..577 CDD:275381 18/54 (33%)
AMN1 <564..>638 CDD:187754 18/69 (26%)
leucine-rich repeat 578..603 CDD:275381 5/24 (21%)
leucine-rich repeat 604..629 CDD:275381 7/24 (29%)
leucine-rich repeat 630..655 CDD:275381 1/3 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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