DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and CG5003

DIOPT Version :10

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster


Alignment Length:388 Identity:81/388 - (20%)
Similarity:127/388 - (32%) Gaps:149/388 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   326 LTDLPFEILLRILSYLDLKSLFRVGHVSRTFYDISRHPLLYAEISLKPYWDVASSEL----LCTL 386
            |.|...|:|..|..|||..|:..|.|.|..|.::......|..|      |:::..|    |..:
  Fly    69 LMDFCDELLFEIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHI------DLSNGPLPMGILEEI 127

  Fly   387 ARRATMLRKLDLSWCGGFGNVSPT------EFKKFLTQRGDNLTHLRLNSC--KFLNASCIENVG 443
            ..|||. :...:..||     .|:      ||::| ||        .|:|.  :.:....:|..|
  Fly   128 LGRATE-KTHTIKICG-----PPSSQHVAGEFRQF-TQ--------TLSSVFPRVVQLKVLELEG 177

  Fly   444 IVCD-----------NLIELSLRNCATE----PPLLNFSCLANLKNLERLDL-----FQTYFETE 488
            :..|           .|..|.|::|:..    |..:.:|...:|.:||.|.:     |:.|:   
  Fly   178 VSLDFEYIHITEFPATLRRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWFEPYY--- 239

  Fly   489 LLLSMLEGNRKLKHLNLAFCGVSVNMDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLAR---- 549
                 :.|..||..|..                                 ||.:|.|:|.:    
  Fly   240 -----IMGLSKLPSLRR---------------------------------LSLKGCQALCKFVPY 266

  Fly   550 --------LHQLEELDLGWCMREASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHI--AALG 604
                    ..:||.|||    |:..:.:...|..|....||:|.|.:.:      ::|.  |...
  Fly   267 GSMAARFGFQKLESLDL----RQTPINNSDLQCFSAIENLKELLLESPQ------ILHSKQAVAK 321

  Fly   605 KNLE----------QLDLMGILN----------ITHERVYDILVNCPKLQLLDLSFCDNIMDR 647
            ||..          |.|.:.:|:          :.|.|...:..|           .||..||
  Fly   322 KNTNGNATDEAASPQPDSLKVLSDDEPSTSRAAMEHLRACKVAFN-----------LDNCSDR 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..370 CDD:463757 14/43 (33%)
leucine-rich repeat 393..422 CDD:275381 8/34 (24%)
leucine-rich repeat 423..442 CDD:275381 3/20 (15%)
LRR <427..>639 CDD:443914 48/267 (18%)
leucine-rich repeat 449..474 CDD:275381 7/28 (25%)
leucine-rich repeat 475..499 CDD:275381 6/28 (21%)
leucine-rich repeat 500..527 CDD:275381 2/26 (8%)
leucine-rich repeat 528..552 CDD:275381 5/35 (14%)
leucine-rich repeat 553..580 CDD:275381 8/26 (31%)
leucine-rich repeat 581..606 CDD:275381 6/26 (23%)
leucine-rich repeat 607..632 CDD:275381 6/44 (14%)
leucine-rich repeat 633..652 CDD:275381 4/15 (27%)
CG5003NP_651593.1 F-box 69..111 CDD:425796 14/41 (34%)
leucine-rich repeat 610..635 CDD:275381
Blue background indicates that the domain is not in the aligned region.

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