DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and Kdm2

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_001262400.1 Gene:Kdm2 / 41090 FlyBaseID:FBgn0037659 Length:1345 Species:Drosophila melanogaster


Alignment Length:446 Identity:100/446 - (22%)
Similarity:160/446 - (35%) Gaps:134/446 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   236 RTVTKTQNLLAKQQITQHSRTLVSP-----PPDAIGSTSGDGSGGSISHKLRTLKFQPNCGEDGA 295
            |.....::.||:|.:...:|.|..|     |....||:|..|:|||.|                |
  Fly   968 RKKNSIRSQLAQQMLNSSTRVLKKPQYVVRPASGTGSSSSSGNGGSAS----------------A 1016

  Fly   296 TKLHEFINNDLSQFLADNCVDGE---------------------AAAPQICLTDLPFEILLRILS 339
            |   ..|:|..:|..|::|..|.                     :::..:.|.....:|:.|   
  Fly  1017 T---NGISNGSNQSGANSCGAGNGERGTNNGGLSGSNGLGNQHYSSSQNLALDPTVLKIIFR--- 1075

  Fly   340 YLDLKSLFRVGHVSRTFYDISRHPLLYAEISLKPYWDVASSELLCTLARRA--------TMLRKL 396
            ||...:|.....|.:.:.:.:..|.|:.:::...:  ..|:.||..:.||.        |.:.|.
  Fly  1076 YLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEH--KMSASLLTAIVRRQPEHLILDWTQIAKR 1138

  Fly   397 DLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVCDNLIELSLRNCATEP 461
            .|:|               |..|...|.:|.|.:|.      |:.|         |:|..|.. |
  Fly  1139 QLAW---------------LVARLPALKNLSLQNCP------IQAV---------LALHTCLC-P 1172

  Fly   462 PL--LNFSCLANLKNLERLDLFQTYFETELLLSMLEGN-RKLKHLNLAFCGVSVNMDNVAAHLAT 523
            ||  |:.|.:..|.:....|:.....::...||..:.. |.||.:.||    ..::.:||..   
  Fly  1173 PLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLA----GTDISDVAVR--- 1230

  Fly   524 YNTQLISLDLWKAHFLSSRGLQSLARLHQLEELDLGWCMREASLGDGLFQL---LSNCPKLKKLF 585
            |.||                     .|..|..|||..|.|....  |:.|:   .:...:|.:|.
  Fly  1231 YITQ---------------------SLPYLRHLDLSSCQRITDA--GVAQIGTSTTATARLTELN 1272

  Fly   586 LSAVRGTTERDLMHIAALGKNLEQLDLMGILNITHERV--------YDILVNCPKL 633
            |||.|..:|..|.|:|.. :.|..|||..:..::.:.|        :|:.|...||
  Fly  1273 LSACRLVSENALEHLAKC-EGLIWLDLRHVPQVSTQSVIRFASNSKHDLCVRDIKL 1327

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 9/45 (20%)
leucine-rich repeat 393..422 CDD:275381 5/28 (18%)
leucine-rich repeat 423..442 CDD:275381 5/18 (28%)
LRR_RI 437..>641 CDD:238064 52/211 (25%)
leucine-rich repeat 449..474 CDD:275381 9/26 (35%)
leucine-rich repeat 475..499 CDD:275381 3/24 (13%)
leucine-rich repeat 500..527 CDD:275381 7/26 (27%)
leucine-rich repeat 528..552 CDD:275381 1/23 (4%)
AMN1 552..>660 CDD:187754 27/93 (29%)
leucine-rich repeat 553..580 CDD:275381 8/29 (28%)
leucine-rich repeat 581..606 CDD:275381 10/24 (42%)
leucine-rich repeat 607..632 CDD:275381 7/32 (22%)
leucine-rich repeat 633..652 CDD:275381 1/1 (100%)
Kdm2NP_001262400.1 cupin_like 231..331 CDD:304367
PRTases_typeI <394..>467 CDD:294217
zf-CXXC 670..716 CDD:251032
PHD_4 721..801 CDD:293471
F-box-like <1073..1108 CDD:289689 7/37 (19%)
leucine-rich repeat 1102..1125 CDD:275381 5/24 (21%)
leucine-rich repeat 1126..1149 CDD:275381 6/37 (16%)
leucine-rich repeat 1150..1173 CDD:275381 9/38 (24%)
AMN1 1166..>1320 CDD:187754 45/185 (24%)
leucine-rich repeat 1174..1213 CDD:275381 7/38 (18%)
leucine-rich repeat 1214..1238 CDD:275381 10/51 (20%)
leucine-rich repeat 1239..1267 CDD:275381 8/29 (28%)
leucine-rich repeat 1268..1292 CDD:275381 10/24 (42%)
leucine-rich repeat 1293..1317 CDD:275381 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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