DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fbxl4 and Skp2

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster


Alignment Length:516 Identity:103/516 - (19%)
Similarity:170/516 - (32%) Gaps:179/516 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   194 LDSRRFAPSLKKTTMLTKTLRIDFNH---------SRLNYYTEIDAIMLCGRTVTKT-------Q 242
            |||...:.|......|..:...|.|.         ||:.:..:....:..|.|...|       .
  Fly    66 LDSEESSSSALSAIALAVSATSDDNSNETTPCASVSRMAHQLQHTQRLSLGSTGDITLDSPAVED 130

  Fly   243 NLLAKQQITQHSRTLVSPPPDAIGSTSGDGSGGSISHKLR----------------TLKFQPNCG 291
            :|...:|..:..:.|......::|| .|.|:..|.|.:||                :|.|||:..
  Fly   131 SLSMSRQSAEKLQILAQAKRSSLGS-EGSGNSNSPSKRLRNPLAAVTCNNQIDGTASLNFQPSTS 194

  Fly   292 EDGATK---------------------------LHEFINNDLSQF--LADNCVDGEAAAPQICLT 327
            .....:                           :...||:.::.|  |:|               
  Fly   195 RLAQVRQAKKPSTTNITTRIVAADSFFVFRTPAMSAHINSGINYFERLSD--------------- 244

  Fly   328 DLPFEILLRILSYLDLKSLFRVGHVSRTFYDISRHPLLYAEISLKPYWDVASSELLCTLARRATM 392
                ||||.|..:|..|:|.|:..|.|.|...||...|:.                         
  Fly   245 ----EILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWT------------------------- 280

  Fly   393 LRKLDLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVCDNLIELSLRNC 457
              :|||    |...:.|...::.:.:                        |::...|.:.|::..
  Fly   281 --RLDL----GLRTIRPGALEQIVRR------------------------GVLVIRLAQTSIQEP 315

  Fly   458 ATEPPLLNFSCLANLKNLERLDLFQTYFETELLLSMLEGNRKLKHLNLAFCGVSVNM-DNVAAHL 521
            |..|....|.     ..|:.|||.........||::|...|:||.::|.    ::.: |::.|.:
  Fly   316 AFAPYTEVFR-----TRLQYLDLSMASITRSSLLTLLSHCRQLKKISLE----NIELDDDICAEI 371

  Fly   522 ATYNTQLISLDLWKAHFLSSRGLQ-SLARLHQLEELDLGWCMREASLGDGLFQLLSNCPKLKKLF 585
            |. |..|.:::|..|..|:|..:: .:..|..|..|::.|....|.....|...:|  |.|.:|.
  Fly   372 AK-NEALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTALVTHIS--PNLIRLN 433

  Fly   586 LSAVRGTTERDLM--HIAALGKNLEQLDLMGILNITHERVYDILVNCPKLQLLDLSFCDNI 644
            ::..|    |.|.  |:|.|.|                       .||:|..||||.|:::
  Fly   434 IAGCR----RVLFDSHVATLQK-----------------------RCPQLLELDLSDCNSL 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 15/45 (33%)
leucine-rich repeat 393..422 CDD:275381 5/28 (18%)
leucine-rich repeat 423..442 CDD:275381 0/18 (0%)
LRR_RI 437..>641 CDD:238064 50/207 (24%)
leucine-rich repeat 449..474 CDD:275381 5/24 (21%)
leucine-rich repeat 475..499 CDD:275381 7/23 (30%)
leucine-rich repeat 500..527 CDD:275381 7/27 (26%)
leucine-rich repeat 528..552 CDD:275381 6/24 (25%)
AMN1 552..>660 CDD:187754 24/95 (25%)
leucine-rich repeat 553..580 CDD:275381 6/26 (23%)
leucine-rich repeat 581..606 CDD:275381 8/26 (31%)
leucine-rich repeat 607..632 CDD:275381 1/24 (4%)
leucine-rich repeat 633..652 CDD:275381 6/12 (50%)
Skp2NP_730815.2 F-box-like 239..284 CDD:289689 19/90 (21%)
leucine-rich repeat 302..327 CDD:275381 5/29 (17%)
AMN1 309..480 CDD:187754 49/198 (25%)
leucine-rich repeat 328..352 CDD:275381 7/23 (30%)
leucine-rich repeat 353..376 CDD:275381 7/27 (26%)
leucine-rich repeat 377..402 CDD:275381 6/24 (25%)
leucine-rich repeat 403..428 CDD:275381 6/26 (23%)
leucine-rich repeat 429..455 CDD:275381 10/52 (19%)
leucine-rich repeat 456..480 CDD:275381 6/12 (50%)
leucine-rich repeat 481..500 CDD:275381
leucine-rich repeat 506..529 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45458003
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.