DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and Fbxl22

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_001102239.1 Gene:Fbxl22 / 363083 RGDID:1311830 Length:236 Species:Rattus norvegicus


Alignment Length:271 Identity:63/271 - (23%)
Similarity:92/271 - (33%) Gaps:83/271 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   326 LTDLPFEILLRILSYLDLKSLFRVGHVSRTFYDISRHPLLYAEISLKPYWDVASSELLCTLARRA 390
            :|.|..|.|||:.|:||..|...:........|:...|.|::.:...     :.:||.....|.:
  Rat     3 ITQLNRECLLRLFSFLDKDSRKSLSRTCSQLRDVFEDPTLWSLLHFH-----SLTELKKDNFRLS 62

  Fly   391 TMLRKLDLSWCGGFGNVSPTE------FKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVCDNL 449
            ..||.|.:.|......|...|      |::.:..:.:||.:      .||...|..     |.||
  Rat    63 PALRSLSICWHSSRVQVCSIEDWLKSAFQRSICSQHENLVN------DFLLQVCNR-----CPNL 116

  Fly   450 IELSLRNCATEPPLLNFSCLANLKNLERLDLFQTYFETELLLSMLEGNRKLKHLNLAFCGVSVN- 513
            ..::|..|..    :...|||.|                     |.|..:|:.|.|..|....| 
  Rat   117 ASVTLSGCGH----VTDDCLARL---------------------LLGCPRLRALRLENCARVTNR 156

  Fly   514 -MDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLARLHQLEELDLGWCMREASLGDGLFQLLSN 577
             :..||||                    .|.||:         ..:.:| |..|.. ||.:|.:.
  Rat   157 TLAAVAAH--------------------GRALQT---------FHVDFC-RNVSAA-GLLRLRAA 190

  Fly   578 CPKLKKLFLSA 588
            ||   .|.|||
  Rat   191 CP---NLILSA 198

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 13/45 (29%)
leucine-rich repeat 393..422 CDD:275381 7/34 (21%)
leucine-rich repeat 423..442 CDD:275381 4/18 (22%)
LRR_RI 437..>641 CDD:238064 36/154 (23%)
leucine-rich repeat 449..474 CDD:275381 7/24 (29%)
leucine-rich repeat 475..499 CDD:275381 2/23 (9%)
leucine-rich repeat 500..527 CDD:275381 9/28 (32%)
leucine-rich repeat 528..552 CDD:275381 3/23 (13%)
AMN1 552..>660 CDD:187754 12/37 (32%)
leucine-rich repeat 553..580 CDD:275381 7/26 (27%)
leucine-rich repeat 581..606 CDD:275381 4/8 (50%)
leucine-rich repeat 607..632 CDD:275381
leucine-rich repeat 633..652 CDD:275381
Fbxl22NP_001102239.1 F-box-like 3..43 CDD:403981 12/39 (31%)
AMN1 44..>191 CDD:187754 44/218 (20%)
leucine-rich repeat 116..141 CDD:275381 9/49 (18%)
leucine-rich repeat 142..167 CDD:275381 9/44 (20%)
leucine-rich repeat 168..193 CDD:275381 10/38 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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