Protein Alignment Fbxl4 and Fbl6

DIOPT Version :9

• Sequence 1: NP_572951.1
• Gene: Fbxl4 / 32378
• FlyBaseID: FBgn0030555
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_610665.2
• Gene: Fbl6 / 36201
• FlyBaseID: FBgn0033609
• Length: 720
• Species: Drosophila melanogaster
• Alignment Length: 871
• Identity: 175/871 - (20%)
• Similarity: 270/871 - (30%)
• Gaps: 364/871 - (41%)

  Fly     2 SLLAYGEPAESSETDSPAAEAEPDVLVDF--TAMLQRQRQNGDYGGWFGCDSKMQTTQSDQGYYL 64
            ||.:..|..:.|:.|....:||.....|.  |||   :.:..|.||       .|..||:
  Fly     4 SLSSQVEETKVSDDDGVKEKAEVSTAKDSAETAM---EVEADDTGG-------QQPEQSE----- 53

  Fly    65 EQYVLGVLDFSSQYGIDYSISYTAANVIGRPTKFPAYGDYPETFPMRTYGDWWQRAPSATREIQP 129
                  :||......:|.: :.|.:.    |::.|     |:...:.|       |.|.:..:.|
  Fly    54 ------LLDKEKSATVDIN-TLTPST----PSQTP-----PQLLAVET-------ATSGSTAVIP 95

  Fly   130 QNL---PKLETHDYVVVYFEEFVVPTEVAIFETFNPGAVVRIWAYGLTKNWTCLWEATESDLSRP 191
            :|:   ||.||..      :|    |..|...:.:|.                      ||..|.
  Fly    96 ENILSPPKSETQT------DE----TNTATSTSCSPA----------------------SDGQRS 128

  Fly   192 PPLDSRRFAP----------------------------SLKKTTML------------TKTLRID 216
            |..|.:..||                            |.|||:..            ||.|.:
  Fly   129 PAADQQSSAPPPQVQAQATPAPVNGSVPKSGKPLSTALSGKKTSKAATTSPRASRCRKTKALPM- 192

  Fly   217 FNHSRLNYYTEID----AIMLCGRTVTKTQNLLAKQQITQHSRTLVSPPPDAIGSTS-------- 269
                   |.:||.    .|.||          :.|....:.:...|:.||.|:.:.:
  Fly   193 -------YESEISDNKMGIRLC----------IKKSDAGEGAPAGVTSPPVAVPAATKTVRKRVR 240

  Fly   270 --------------------GDGSGGSISHKLRTLKFQPNCGEDGATKLHEFINNDLSQFLADNC 314
                                |.||||.     :.:...|:..|
  Fly   241 KPKQQDSDEAEYEPRKKKGGGGGSGGE-----KKVSTSPDAAE---------------------- 278

  Fly   315 VDGEAAAPQICLTDLPFEILLRILSY-LD----LKSLFRVGHVSRTFYDISRHPLLY-------- 366
            ..|:.....:....||.|:|.||..: :|    |.:|||:|.|...:..:|..|.|:
  Fly   279 AAGDPVEQSVWAQKLPEEVLFRIFEHAVDTQGCLPTLFRLGRVCSLWRQVSLRPTLWRTMDLTTW 343

  Fly   367 ------AEISLKPY---------------WDVASSELLCTLARRAT------------------- 391
                  .|:.||.:               |.:  |::.|.||:.::
  Fly   344 VKEKYRTELKLKWFVDNRCSACTDLNVSNWKI--SDINCFLAKLSSGCPNLAGITLSGWKGFTSD 406

  Fly   392 ----------MLRKLDLSWCGGFGNVSPT-----EFKKFLTQRGDNLTHLRLNSCKFLNASCIEN 441
                      .|::||||......|.|.:     .....|...|..||||.|...:.  |...:.
  Fly   407 HLTYLVDNMHKLQRLDLSSINVEMNASKSAVGVNSLCNALQTMGSRLTHLYLAHNRL--AGIPQI 469

  Fly   442 VGIV---CDNLIELSLRNCATEP--------PLLNFSC----------------LANLK------ 473
            |||:   |.||..|.|.|..|:.        ..|...|                .|:::
  Fly   470 VGILSTHCPNLTLLDLSNVTTQATSHGVLHIEKLQRGCQKLKVLRVTNSHITPSTASMQEIMDSP 534

  Fly   474 ---NLERLDLFQTYFETEL-----LLSMLEGNRKLKHLNLAFCGVSVNMDNVAAHLATYNTQLIS 530
               .||.|.:.....|:.:     |..:|:.:.|||.|::..|            ....:..||.
  Fly   535 GFPELEELSVAALTDESRIISDDHLQRILKSSSKLKLLDVRNC------------TRLTHESLIR 587

  Fly   531 LDLW--KAHFLS--------SRGLQSLAR--LHQLEELDLGWCMREASLGDGLFQLLSNCPKLKK 583
            |..|  |..|||        ..||:.:|.  .|.|.||||.|.        .:.|.:.|
  Fly   588 LPAWDIKHLFLSGCSVTRDMGSGLELIASKWAHSLIELDLAWA--------NMQQPIDN------ 638

  Fly   584 LFLSAVRGTTERDLMHIAALGKN--LEQLDLMGILNITHERVYDILVNCPKLQLLDLSFCDNI-- 644
                |:|...|:        |::  |..|:|.| .:::.|.|.:||.||..:..::|:.|..:
  Fly   639 ----ALRALAEK--------GRDSPLAHLNLCG-SSVSDEAVKEILTNCQNMSSINLASCRGLPR 690

  Fly   645 ----MDRDFDLLAEWSRQFKVDIKSS 666
                :.:....|.|......|.:|||
  Fly   691 GVKRLMQGPQELGELREVLGVQLKSS 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl4	NP_572951.1	F-box-like	326..372	CDD:289689	17/64 (27%)
		leucine-rich repeat	393..422	CDD:275381	9/33 (27%)
		leucine-rich repeat	423..442	CDD:275381	6/18 (33%)
		LRR_RI	437..>641	CDD:238064	59/258 (23%)
		leucine-rich repeat	449..474	CDD:275381	8/57 (14%)
		leucine-rich repeat	475..499	CDD:275381	6/28 (21%)
		leucine-rich repeat	500..527	CDD:275381	4/26 (15%)
		leucine-rich repeat	528..552	CDD:275381	11/35 (31%)
		AMN1	552..>660	CDD:187754	26/115 (23%)
		leucine-rich repeat	553..580	CDD:275381	8/26 (31%)
		leucine-rich repeat	581..606	CDD:275381	4/24 (17%)
		leucine-rich repeat	607..632	CDD:275381	10/24 (42%)
		leucine-rich repeat	633..652	CDD:275381	2/24 (8%)
Fbl6	NP_610665.2	F-box-like	293..341	CDD:289689	16/47 (34%)
		leucine-rich repeat	365..391	CDD:275381	5/27 (19%)
		leucine-rich repeat	392..417	CDD:275381	0/24 (0%)
		leucine-rich repeat	418..445	CDD:275381	7/26 (27%)
		leucine-rich repeat	453..471	CDD:275381	6/19 (32%)
		leucine-rich repeat	480..509	CDD:275381	7/28 (25%)
		leucine-rich repeat	510..538	CDD:275381	1/27 (4%)
		leucine-rich repeat	539..579	CDD:275381	11/51 (22%)
		leucine-rich repeat	580..621	CDD:275381	11/40 (28%)
		leucine-rich repeat	622..649	CDD:275381	12/52 (23%)
		leucine-rich repeat	652..676	CDD:275381	10/24 (42%)
		leucine-rich repeat	677..698	CDD:275381	2/20 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810