DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and Fbxl19

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_006230338.1 Gene:Fbxl19 / 308999 RGDID:1310989 Length:739 Species:Rattus norvegicus


Alignment Length:300 Identity:71/300 - (23%)
Similarity:106/300 - (35%) Gaps:70/300 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   329 LPFEILLRILSYLDLKSLFRVGHVSRTF------------YDISRHPLLYAEISLKPYWDVASSE 381
            ||....||:..:|..:.|.....|.||:            .|:||..      ||.|       .
  Rat   469 LPRAAWLRVFQHLGPRELCVCMRVCRTWSRWCYDKRLWPRMDLSRRK------SLTP-------P 520

  Fly   382 LLCTLARRATMLRKLDLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVC 446
            :|..:.||..  |.|||||.|    ||..:. .:|..|...|..|.|:.|.:|:.|.:.:..:..
  Rat   521 MLSGVVRRQP--RALDLSWTG----VSKKQL-MWLLNRLQGLQELVLSGCSWLSVSALGSAPLPA 578

  Fly   447 DNLIEL---------SLRNCATEPPLL---NFSCLANLKNLERLDLFQTYFETELLLSMLEGNRK 499
            ..|::|         .||.....||..   .......|:.:..|.|.........|..:|....:
  Rat   579 LRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLELTDASLRLLLRHAPQ 643

  Fly   500 LKHLNLAFCGVSVNMDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLARLHQLEELDLGWCMRE 564
            |..|:|:.|   .::.:.:.||.|..|..:.                    ..|..|:|..|.| 
  Rat   644 LSALDLSHC---AHVGDPSVHLLTAPTSPLR--------------------ETLVHLNLAGCHR- 684

  Fly   565 ASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHIAALG 604
              |.|....|...||:|::|.|.:.|..:......:||.|
  Rat   685 --LTDHCLPLFRRCPRLRRLDLRSCRQLSPEACARLAAAG 722

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 13/54 (24%)
leucine-rich repeat 393..422 CDD:275381 11/28 (39%)
leucine-rich repeat 423..442 CDD:275381 6/18 (33%)
LRR_RI 437..>641 CDD:238064 36/179 (20%)
leucine-rich repeat 449..474 CDD:275381 7/36 (19%)
leucine-rich repeat 475..499 CDD:275381 4/23 (17%)
leucine-rich repeat 500..527 CDD:275381 7/26 (27%)
leucine-rich repeat 528..552 CDD:275381 0/23 (0%)
AMN1 552..>660 CDD:187754 16/52 (31%)
leucine-rich repeat 553..580 CDD:275381 9/26 (35%)
leucine-rich repeat 581..606 CDD:275381 6/23 (26%)
leucine-rich repeat 607..632 CDD:275381
leucine-rich repeat 633..652 CDD:275381
Fbxl19XP_006230338.1 zf-CXXC <95..122 CDD:251032
PHD_FXL19 132..193 CDD:277115
F-box-like 469..512 CDD:289689 10/42 (24%)
AMN1 511..710 CDD:187754 58/244 (24%)
leucine-rich repeat 531..554 CDD:275381 11/27 (41%)
leucine-rich repeat 555..578 CDD:275381 6/22 (27%)
leucine-rich repeat 616..643 CDD:275381 5/26 (19%)
leucine-rich repeat 644..670 CDD:275381 8/28 (29%)
leucine-rich repeat 674..698 CDD:275381 9/26 (35%)
leucine-rich repeat 699..723 CDD:275381 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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