DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl4 and Kdm2b

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_038945396.1 Gene:Kdm2b / 304495 RGDID:1310217 Length:1350 Species:Rattus norvegicus


Alignment Length:557 Identity:106/557 - (19%)
Similarity:175/557 - (31%) Gaps:216/557 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   185 ESDLSRPPPL-----DSRRFAPSL-------------KKTTM----------LTKTLRIDFNHSR 221
            |.||...||.     .||..:|:.             :|..|          |:|.|..:.||. 
  Rat   908 EDDLPEAPPKTRESDQSRSSSPTAGPSTEGAEGPEEKRKVKMRRKRRLPNKELSKELSKELNHE- 971

  Fly   222 LNYYTEIDAIMLCGRTVTKTQNLLA------------------KQQIT----------------- 251
                            :.||::.||                  |:.::                 
  Rat   972 ----------------IQKTESTLAHENHQPIKSEPESENEEPKRPLSHCERPHRFSKGLNGTPR 1020

  Fly   252 --QHS---------RTLVSPPPDAIGSTSGDGSGGSISHKLRTLKFQPNCG----EDGATK-LHE 300
              :||         |.:..|||    |||.........|.:|.....|...    :|||.. :|.
  Rat  1021 ELRHSLGPGLRSPPRVISRPPP----STSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHR 1081

  Fly   301 FINNDLSQFLADNCVDGEAAAPQICLTDLPFEILLRILSYLDLKSLFRVGHVSRTFYDISRHPLL 365
                                           |:.:.:.|||..:.|.....|.||:........|
  Rat  1082 -------------------------------EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRL 1115

  Fly   366 YAEISLKPYWDVASSELLCTLARRATMLRKLDLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNS 430
            :..|.|. :....:..:|..:.||..:  .|||||.    |:|..:. .:|..|...|..|.|:.
  Rat  1116 WTRIDLN-HCKSITPLMLSGIIRRQPV--SLDLSWT----NISKKQL-SWLINRLPGLRDLVLSG 1172

  Fly   431 CKFLNASCIENVGIVCDNLIELSLRNCATEPPL---LNFSCLANLKNLERLDLFQTYFETELLLS 492
            |.::..|.:                 |::..||   |:...:..||:.:..||...  .|:....
  Rat  1173 CSWIAVSAL-----------------CSSSCPLLRTLDVQWVEGLKDAQMRDLLSP--PTDNRPG 1218

  Fly   493 MLEGNRKLKHLNLAFCGVSVNMDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLARLHQLEELD 557
            .::...||:::             |...||..:...:||.|...|      :..|::||      
  Rat  1219 QMDNRSKLRNI-------------VELRLAGLDITDVSLRLIIRH------MPLLSKLH------ 1258

  Fly   558 LGWC--MREASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHIAALGKNLEQLDLMGILNITH 620
            |.:|  :.:.|:.                .|:|| |||.||         :|.:::|.....:| 
  Rat  1259 LSYCNHVTDQSIN----------------LLTAV-GTTTRD---------SLTEINLSDCNKVT- 1296

  Fly   621 ERVYDILVNCPKLQLLDLSFCDNIMDRDFD-LLAEWS 656
            ::.......|..:..:||.:|..:.....: .:||.|
  Rat  1297 DQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMS 1333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 10/45 (22%)
leucine-rich repeat 393..422 CDD:275381 9/28 (32%)
leucine-rich repeat 423..442 CDD:275381 5/18 (28%)
LRR_RI 437..>641 CDD:238064 39/208 (19%)
leucine-rich repeat 449..474 CDD:275381 5/27 (19%)
leucine-rich repeat 475..499 CDD:275381 3/23 (13%)
leucine-rich repeat 500..527 CDD:275381 4/26 (15%)
leucine-rich repeat 528..552 CDD:275381 6/23 (26%)
AMN1 552..>660 CDD:187754 21/108 (19%)
leucine-rich repeat 553..580 CDD:275381 3/28 (11%)
leucine-rich repeat 581..606 CDD:275381 8/24 (33%)
leucine-rich repeat 607..632 CDD:275381 4/24 (17%)
leucine-rich repeat 633..652 CDD:275381 3/19 (16%)
Kdm2bXP_038945396.1 JmjC 151..226 CDD:214721
cupin_RmlC-like 198..304 CDD:424065
JHD 303..>338 CDD:407680
CTD_KDM2B 476..584 CDD:412026
zf-CXXC <626..662 CDD:366873
PHD_KDM2B 672..733 CDD:277114
PTZ00449 <731..967 CDD:185628 13/58 (22%)
F-box-like 1082..1120 CDD:403981 9/37 (24%)
leucine-rich repeat 1116..1140 CDD:275381 5/24 (21%)
AMN1 1132..1321 CDD:187754 56/266 (21%)
leucine-rich repeat 1141..1164 CDD:275381 9/29 (31%)
leucine-rich repeat 1165..1188 CDD:275381 6/39 (15%)
leucine-rich repeat 1189..1228 CDD:275381 8/40 (20%)
leucine-rich repeat 1229..1253 CDD:275381 7/42 (17%)
leucine-rich repeat 1254..1283 CDD:275381 14/60 (23%)
leucine-rich repeat 1284..1308 CDD:275381 4/24 (17%)
leucine-rich repeat 1309..1333 CDD:275381 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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