DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fbxl4 and Fbxl19

DIOPT Version :9

Sequence 1:NP_572951.1 Gene:Fbxl4 / 32378 FlyBaseID:FBgn0030555 Length:669 Species:Drosophila melanogaster
Sequence 2:XP_036008913.1 Gene:Fbxl19 / 233902 MGIID:3039600 Length:696 Species:Mus musculus


Alignment Length:300 Identity:71/300 - (23%)
Similarity:106/300 - (35%) Gaps:70/300 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   329 LPFEILLRILSYLDLKSLFRVGHVSRTF------------YDISRHPLLYAEISLKPYWDVASSE 381
            ||....||:..:|..:.|.....|.||:            .|:||..      ||.|       .
Mouse   426 LPRAAWLRVFQHLGPRELCVCMRVCRTWSRWCYDKRLWPRMDLSRRK------SLTP-------P 477

  Fly   382 LLCTLARRATMLRKLDLSWCGGFGNVSPTEFKKFLTQRGDNLTHLRLNSCKFLNASCIENVGIVC 446
            :|..:.||..  |.|||||.|    ||..:. .:|..|...|..|.|:.|.:|:.|.:.:..:..
Mouse   478 MLSGVVRRQP--RALDLSWTG----VSKKQL-MWLLNRLQGLQELVLSGCSWLSVSALGSAPLPA 535

  Fly   447 DNLIEL---------SLRNCATEPPLL---NFSCLANLKNLERLDLFQTYFETELLLSMLEGNRK 499
            ..|::|         .||.....||..   .......|:.:..|.|.........|..:|....:
Mouse   536 LRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLELTDASLRLLLRHAPQ 600

  Fly   500 LKHLNLAFCGVSVNMDNVAAHLATYNTQLISLDLWKAHFLSSRGLQSLARLHQLEELDLGWCMRE 564
            |..|:|:.|   .::.:.:.||.|..|..:.                    ..|..|:|..|.| 
Mouse   601 LSALDLSHC---AHVGDPSVHLLTAPTSPLR--------------------ETLVHLNLAGCHR- 641

  Fly   565 ASLGDGLFQLLSNCPKLKKLFLSAVRGTTERDLMHIAALG 604
              |.|....|...||:|::|.|.:.|..:......:||.|
Mouse   642 --LTDHCLPLFRRCPRLRRLDLRSCRQLSPEACARLAAAG 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl4NP_572951.1 F-box-like 326..372 CDD:289689 13/54 (24%)
leucine-rich repeat 393..422 CDD:275381 11/28 (39%)
leucine-rich repeat 423..442 CDD:275381 6/18 (33%)
LRR_RI 437..>641 CDD:238064 36/179 (20%)
leucine-rich repeat 449..474 CDD:275381 7/36 (19%)
leucine-rich repeat 475..499 CDD:275381 4/23 (17%)
leucine-rich repeat 500..527 CDD:275381 7/26 (27%)
leucine-rich repeat 528..552 CDD:275381 0/23 (0%)
AMN1 552..>660 CDD:187754 16/52 (31%)
leucine-rich repeat 553..580 CDD:275381 9/26 (35%)
leucine-rich repeat 581..606 CDD:275381 6/23 (26%)
leucine-rich repeat 607..632 CDD:275381
leucine-rich repeat 633..652 CDD:275381
Fbxl19XP_036008913.1 zf-CXXC <52..79 CDD:366873
PHD_FXL19 89..150 CDD:277115
F-box-like 426..467 CDD:403981 9/40 (23%)
AMN1 468..667 CDD:187754 58/244 (24%)
leucine-rich repeat 488..511 CDD:275381 11/27 (41%)
leucine-rich repeat 512..535 CDD:275381 6/22 (27%)
leucine-rich repeat 573..600 CDD:275381 5/26 (19%)
leucine-rich repeat 601..627 CDD:275381 8/28 (29%)
leucine-rich repeat 631..655 CDD:275381 9/26 (35%)
leucine-rich repeat 656..680 CDD:275381 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.