DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1434 and SMM1

DIOPT Version :9

Sequence 1:	NP_001285237.1	Gene:	CG1434 / 32377	FlyBaseID:	FBgn0030554	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_014412.1	Gene:	SMM1 / 855749	SGDID:	S000005298	Length:	384	Species:	Saccharomyces cerevisiae

Alignment Length:	380	Identity:	124/380 - (32%)
Similarity:	198/380 - (52%)	Gaps:	58/380 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGTVDFVDPS----- 81
            |..||:||||||.|.||.||:||..|||:|::.|::|.|||:.:|:.|.||.|||:|.||
Yeast     4 YAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCVRKENTALQTVDYVVPSKVQTR 68

  Fly    82 DGTIVFRTCAQ-ETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLA 145
            ..|:||||..: |:|:|:.|:|::....|......:..|:||:|||.||||.|||..|||:|||.
Yeast    69 PETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLR 133

  Fly   146 DPDKAAHILRTLCSGL----DIPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRD----E 202
            .||....||:.|...:    ..|::.|||:|...:.|:.||::|.||||..:.:|.|..:    |
Yeast   134 TPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNRE 198

  Fly   203 RPQHPAHPEVLRAVAQAVDIPIIANGGSKNMHCYDDLRKFQMECGADSVMVARAAQINVSIF--- 264
            :|......|:.. :.||.::.:|.||..::...:.||:....:......|:|..|:.:.::|
Yeast   199 QPITDYIAEIYE-ICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHT 262

  Fly   265 ------RPEGLLPMDELIEKYLRLCVDYDNAPHNAKYCVQSILRELQETPRGKR-----FLQCQT 318
                  .|..::...|    :::....:||...|.||.:..|:       .||.     |.:|::
Yeast   263 SKPSEDGPSWVVACRE----FIQWATKFDNHIGNTKYMLSRIV-------PGKSVFFQYFARCKS 316

  Fly   319 LQQICEIWELGDYCRRKQRELKTMGNSGRAEVEPPEAL----AKRQKLEDA-AIA 368
            .:::..:             ||.:.:.|.|:.:|.|.|    |:.:.|::| |||
Yeast   317 PEEVSFV-------------LKQLNDDGSAQTDPSEYLENCRAQEKALKNANAIA 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1434	NP_001285237.1	DusA	14..287	CDD:223120	101/287 (35%)
		DUS_like_FMN	25..266	CDD:239200	98/263 (37%)
		Rnc	<317..461	CDD:223644	13/57 (23%)
		DSRM	395..457	CDD:238007
SMM1	NP_014412.1	TIM	31..355	CDD:419668	102/348 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346546
Domainoid	1	1.000	129	1.000	Domainoid score	I1148
eggNOG	1	0.900	-	-		E1_COG0042
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1002
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004414
OrthoInspector	1	1.000	-	-		oto100223
orthoMCL	1	0.900	-	-		OOG6_102617
Panther	1	1.100	-	-	LDO	PTHR45936
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2098
SonicParanoid	1	1.000	-	-		X3701
TreeFam	1	0.960	-	-
	13	12.780