DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1434 and CG10463

DIOPT Version :9

Sequence 1:	NP_001285237.1	Gene:	CG1434 / 32377	FlyBaseID:	FBgn0030554	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_610000.1	Gene:	CG10463 / 35264	FlyBaseID:	FBgn0032819	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	89/378 - (23%)
Similarity:	157/378 - (41%)	Gaps:	80/378 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSI-------RRPNPALGTVDF 77
            :|:|.||:|:|:..:|.||.|.:..|.||||...|......|:|.:       :|
  Fly   253 VDFREKLVLSPLTTLGNLPFRRICKEFGADITCGEMACAQPLLKGMGQEWALTKR---------- 307

  Fly    78 VDPSDGTIVFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAA 142
             ..|:.....:.|....:.|      :.|  |..:.:..|.|.  :|:|:|||.:...:.|.|:|
  Fly   308 -HQSEDVFGVQLCGNNPNML------NQA--AQVIHETAQVDF--IDLNIGCPIDLIYQQGGGSA 361

  Fly   143 LLADPDKAAHILRTL---CSGLD--IPVTCKIR--ILPDVEGTIDLVQKLAATGIAAIGIHARTR 200
            |:    :..:||...   |:.|.  :|.|.|:|  |..|.....:|:..:...|.:|:.:|.|:|
  Fly   362 LM----RRTNILELTVRSCAALSDRLPFTVKMRTGIYADKSVAHELLPLVEEWGASAVTLHGRSR 422

  Fly   201 DER-PQHPAHPEVLRAVAQAVDIPIIANGGSKNMHCYDD-LRKFQMECGADSVMVARAAQINVSI 263
            ::| .:|.....:....|:|..:|:|.||   ::..|:| :.:..:.....|||:.|.|.|...|
  Fly   423 EQRYTKHANWAYIEECAAKAKCMPVIGNG---DILSYEDYMERRTLAPHVCSVMIGRGALIKPWI 484

  Fly   264 FR----PEGLLPMD----ELIEKYLRLCVDYDNAPHNAKYCVQSILRE------------LQETP 308
            |:    .:...|..    |:::|:....:::..:........:..|.|            ||..|
  Fly   485 FQEIKEKQAWSPSSGQRYEMLQKFCNYGLEHWGSDTKGVETTRRFLLEWQSFLYRYIPEALQTAP 549

  Fly   309 RGKRFLQCQTLQQICEIWELGDYCRRKQRELKTMGNSGRAE--VEPPEALAKR 359
            ..|...:.|..              |.:.|::|:.:||.|.  |:..|:|..|
  Fly   550 PQKINARPQKY--------------RGRDEMETLMSSGNAADWVKLSESLLGR 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1434	NP_001285237.1	DusA	14..287	CDD:223120	72/290 (25%)
		DUS_like_FMN	25..266	CDD:239200	67/260 (26%)
		Rnc	<317..461	CDD:223644	11/45 (24%)
		DSRM	395..457	CDD:238007
CG10463	NP_610000.1	DusA	253..547	CDD:223120	75/321 (23%)
CG10463	NP_610000.1	DUS_like_FMN	258..492	CDD:239200	67/261 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0042
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740