DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1434 and Dus2

DIOPT Version :9

Sequence 1:	NP_001285237.1	Gene:	CG1434 / 32377	FlyBaseID:	FBgn0030554	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001099651.1	Gene:	Dus2 / 291978	RGDID:	1305612	Length:	493	Species:	Rattus norvegicus

Alignment Length:	457	Identity:	228/457 - (49%)
Similarity:	302/457 - (66%)	Gaps:	21/457 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGTVDFVDPSDGT 84
            |.|.|||||||||||||||||||||:.||||||.|||:|:|:::..|..|..|.|||||.|.| .
  Rat     8 LCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMLQCRRVVNEVLSTVDFVAPDD-R 71

  Fly    85 IVFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLADPDK 149
            :|||||.:|.||:|.|||||||.|||||.:|::.|::|:|:|||||||:|.|||||||||:||||
  Rat    72 VVFRTCEREQSRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDK 136

  Fly   150 AAHILRTLCSGLDIPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRDERPQHPAHPEVLR 214
            ...||.||..|...||||||||||.:|.|::||:::..|||:||.:|.|.||||||||...||:|
  Rat   137 IEKILSTLVKGTHRPVTCKIRILPSLEDTLNLVKRIERTGISAIAVHGRNRDERPQHPVSCEVIR 201

  Fly   215 AVAQAVDIPIIANGGS-KNMHCYDDLRKFQMECGADSVMVARAAQINVSIFRPEGLLPMDELIEK 278
            |:|:.:.||:|||||| .::..:.|:..|:....|.||||||||..|.|||..:||.|::|:::|
  Rat   202 AIAETLSIPVIANGGSHDHIQQHLDIEDFRQATAASSVMVARAAMWNPSIFLKDGLRPLEEVMQK 266

  Fly   279 YLRLCVDYDNAPHNAKYCVQSILRELQETPRGKRFLQCQTLQQICEIWELGDYCRRKQRELKTMG 343
            |:|..|.|||...|.|||:..:|||..|:|:|:.....|:.|:|||.:.||.:.....|||
  Rat   267 YIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRMLHAAQSSQEICEAFGLGTFYEDTIREL---- 327

  Fly   344 NSGRAEV--EPPEALAKRQKLEDAAIAITDEYDGIICRHMPFLRSTYPSDNHLPKTQLYVHAVKT 406
            ::.||::  :.|||      :|:.|    ::..|||...:.|.|..|| ....|||.|.....:.
  Rat   328 DARRADLLAKTPEA------VEEPA----EDTSGIIKMAIRFDRRAYP-PQITPKTCLLEWCRRE 381

  Fly   407 GKSPPAYETQQ--CDKLFRSICTYDGQRFSSSFWEKNKKQAEQGAALVALLHLGQLEAEVLRDNG 469
            ....|.|||.|  .|::|.|:.|...|::.|:.|:|:||.|||.||:|.|...|..|..:..:|.
  Rat   382 KLPQPVYETVQRPIDRMFCSVVTVAEQKYQSTLWDKSKKLAEQTAAIVCLRSQGLPEGRLGEENP 446

  Fly   470 SL 471
            ||
  Rat   447 SL 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1434	NP_001285237.1	DusA	14..287	CDD:223120	160/267 (60%)
		DUS_like_FMN	25..266	CDD:239200	149/241 (62%)
		Rnc	<317..461	CDD:223644	51/147 (35%)
		DSRM	395..457	CDD:238007	26/63 (41%)
Dus2	NP_001099651.1	DUS_like_FMN	13..252	CDD:239200	147/239 (62%)
Dus2	NP_001099651.1	DSRM_DUS2L	369..436	CDD:380700	26/66 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353851
Domainoid	1	1.000	288	1.000	Domainoid score	I1514
eggNOG	1	0.900	-	-		E1_COG0042
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6838
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1872
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D317470at33208
OrthoFinder	1	1.000	-	-		FOG0004414
OrthoInspector	1	1.000	-	-		oto98499
orthoMCL	1	0.900	-	-		OOG6_102617
Panther	1	1.100	-	-	LDO	PTHR45936
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3701
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760