DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1434 and Dus1l

DIOPT Version :9

Sequence 1:	NP_001285237.1	Gene:	CG1434 / 32377	FlyBaseID:	FBgn0030554	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_742015.2	Gene:	Dus1l / 246185	RGDID:	708389	Length:	475	Species:	Rattus norvegicus

Alignment Length:	412	Identity:	105/412 - (25%)
Similarity:	176/412 - (42%)	Gaps:	88/412 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIK--SIRRPNPALGTVDFVDPSDGTIVFRT 89
            ::||||....|..|||:...||.:.||..|.....::  :.|:.|....    |.|.|..::.:.
  Rat    20 VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCD----VCPEDRPLIVQF 80

  Fly    90 CAQETSRLVLQMGTSDAGRALAVGKLLQRD-ISGLDINMGCPKEFSIKGGMGAALLADPDKAAHI 153
            ||.:....|             ...||.:| ...:|:|:|||:..:.:|..||.|..:.|....:
  Rat    81 CANDPEVFV-------------QAALLAQDYCDAIDLNLGCPQMIAKRGRYGAFLQEEWDLLQRM 132

  Fly   154 LRTLCSGLDIPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRDER-PQ-HPAHPEVLRAV 216
            :......|.:|||||||:.|:::.|:...|.|...|...:.:|.||:::: |. ..|..|.::||
  Rat   133 ILLAHERLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAV 197

  Fly   217 AQAVDIPIIANGGSKNMHCYDDLRKFQMECGADSVMVARAAQINVSIFRPEGLLP-MDELIEKYL 280
            .:||.||:.|||   |:.|..|:.:...:.|...||.|.....|.::|  ||..| :.||.::||
  Rat   198 RKAVGIPVFANG---NIRCLQDVERCIQDTGVQGVMSAEGNLHNPALF--EGRSPAVWELADEYL 257

  Fly   281 RLCVDYDNAPHNAKYCVQSILRELQETPRGKRFLQCQTLQQICEIW----ELGDYCRRKQRELKT 341
            .:...:.        |..|.:|                 ..:.::|    ::....|.:..::||
  Rat   258 DIVRQHP--------CPLSYVR-----------------AHLFKLWHHTLQVHQQLREELAKVKT 297

  Fly   342 MGNSGRAEVEPPEALAKRQKLEDAAIAITDEYDGI-----------ICRHMPFLRSTYPSDNHLP 395
            :  .|.|.|.  :||..|.: ||.|    .:.:|:           ||:  |::|   |......
  Rat   298 L--EGVAAVS--QALKLRCQ-EDMA----RQQEGVRPADNLPAFHWICQ--PYIR---PGPKEGS 348

  Fly   396 KTQLYVHAVKTGKSPPAYETQQ 417
            |..      .:|:|..|.|.::
  Rat   349 KEN------SSGRSKRALEEEE 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1434	NP_001285237.1	DusA	14..287	CDD:223120	78/265 (29%)
		DUS_like_FMN	25..266	CDD:239200	71/243 (29%)
		Rnc	<317..461	CDD:223644	24/116 (21%)
		DSRM	395..457	CDD:238007	5/23 (22%)
Dus1l	NP_742015.2	DUS_like_FMN	18..250	CDD:239200	74/251 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	343..387		5/28 (18%)
		put_zinc_LRP1	396..>431	CDD:130684
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0042
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810