DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL38 and PEBP1

DIOPT Version :9

Sequence 1:	NP_511152.2	Gene:	mRpL38 / 32375	FlyBaseID:	FBgn0030552	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_002558.1	Gene:	PEBP1 / 5037	HGNCID:	8630	Length:	187	Species:	Homo sapiens

Alignment Length:	182	Identity:	48/182 - (26%)
Similarity:	86/182 - (47%)	Gaps:	23/182 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PRVPLNISYQLDGDSLAPVYNGNVIKPTEAAKAP-QIDFDGLVDPITGQAAGQDTYWTLVASNPD 207
            |:.||:::|.  |.::..:  |.|:.||:....| .|.:|||         .....:|||.::||
Human    21 PQHPLHVTYA--GAAVDEL--GKVLTPTQVKNRPTSISWDGL---------DSGKLYTLVLTDPD 72

  Fly   208 AHYTNGT--AECLHWFIANIPNGKVSEGQVLAEYLPPFPPRGVGYQRMVFVLYKQQARLDLGSYQ 270
            |......  .|..|:.:.|:....:|.|.||::|:...||:|.|..|.|:::|:|...|......
Human    73 APSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPI 137

  Fly   271 LA--AADYGNLEKRTFSTLDFYRQHQEQLTPAGLAFYQTNWDESLTQFYHDV 320
            |:  :.|:    :..|....|.::::.:...||.. ||..||:.:.:.|..:
Human   138 LSNRSGDH----RGKFKVASFRKKYELRAPVAGTC-YQAEWDDYVPKLYEQL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL38	NP_511152.2	PEBP_euk	146..307	CDD:176644	43/165 (26%)
PEBP1	NP_002558.1	PEBP_euk	23..171	CDD:176644	43/165 (26%)
PEBP1	NP_002558.1	Interaction with RAF1. /evidence=ECO:0000269\|PubMed:18294816	93..134		14/40 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1881
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557122at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820