DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and SCARF2

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_699165.3	Gene:	SCARF2 / 91179	HGNCID:	19869	Length:	871	Species:	Homo sapiens

Alignment Length:	323	Identity:	76/323 - (23%)
Similarity:	96/323 - (29%)	Gaps:	111/323 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 CAQFERGRCVDMA--CICTARGSGERVPCTPLEERLKLTNIIGGACPCPMPNAICHTRWQQCHCS 97
            |:....|:|.|:.  |.|.||..|.|  |.             .||.|  .:..||.|...|.|.
Human   126 CSCHPHGQCEDVTGQCTCHARRWGAR--CE-------------HACQC--QHGTCHPRSGACRCE 173

  Fly    98 EGHVSSDDRRRCLPAVV----PVGGSCEFQQQCQRADRFSSCIGNQCLC-LNQFEFHEGRCLSVL 157
            .|...:.....|..:..    |..|:|    .|.......|| .|||.| .:..|...|||
Human   174 PGWWGAQCASACYCSATSRCDPQTGAC----LCHAGWWGRSC-NNQCACNSSPCEQQSGRC---- 229

  Fly   158 QSSCLE-------DKDCGSCGASICLTKTKRCGCSKNFVHNHNMTKCIKGSAYG-------DTCE 208
              .|.|       |:.| .|....|......|.|...:...:....|..| .||       ..|:
Human   230 --QCRERTFGARCDRYC-QCFRGRCHPVDGTCACEPGYRGKYCREPCPAG-FYGLGCRRRCGQCK 290

  Fly   209 HSSPCKLNLGADGRCLDHLC-----------VCRSTHYPKRVANEVAKDENDDLDAVNNLERITC 262
            ...||.:   |:||||  .|           .|.:..|.:..::.                   |
Human   291 GQQPCTV---AEGRCL--TCEPGWNGTKCDQPCATGFYGEGCSHR-------------------C 331

  Fly   263 APIVPFGALCRNDSECRMQPMDQENATASIGHPMVCNWG------ECSCSKTHRLEDNKCVFV 319
            .|       ||:...|       .:.|   |....||.|      |..||.....||  |.||
Human   332 PP-------CRDGHAC-------NHVT---GKCTRCNAGWIGDRCETKCSNGTYGED--CAFV 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	15/61 (25%)
SCARF2	NP_699165.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		PHA03247	<534..871	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	570..871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900