DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and SCARF1

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_003684.2	Gene:	SCARF1 / 8578	HGNCID:	16820	Length:	830	Species:	Homo sapiens

Alignment Length:	224	Identity:	58/224 - (25%)
Similarity:	76/224 - (33%)	Gaps:	61/224 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CSSDAQCAQFERGRCVDMACICTA----RGSGERVPCTPLEERLKLTNIIGGAC----PCPMPNA 85
            |....:|.   ||||...:..||.    ||:...:||......::..:.. |.|    ||.....
Human   219 CQQQCECV---RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC-GRCKHNEPCSPDTG 279

  Fly    86 ICHTRWQQCHCSEGHVSSDDRRRCLPAVVPVGGSCEFQQQCQRADRFSSCIGNQCLCLNQFEFHE 150
            .|.:      |..|...:..::.|||..  .|.|||  |||.......:|           |...
Human   280 SCES------CEPGWNGTQCQQPCLPGT--FGESCE--QQCPHCRHGEAC-----------EPDT 323

  Fly   151 GRCLSV----LQSSCLED--------KDCGS----CGASICLTKTKRCGCSKNFVHNHNMTKCIK 199
            |.|...    |...| ||        :||||    |....|.|.|..|.||..:........|..
Human   324 GHCQRCDPGWLGPRC-EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPA 387

  Fly   200 GSAYGDTCEHSSPCKLNLGADGRCLDHLC 228
            | .:|:.|  |.||:        |.:.||
Human   388 G-FHGNNC--SVPCE--------CPEGLC 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	15/56 (27%)
SCARF1	NP_003684.2	CSRNP_N	<100..135	CDD:292638
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	516..539
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	581..688
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	715..830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900