DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11674 and Megf10

DIOPT Version :9

Sequence 1:NP_572948.1 Gene:CG11674 / 32374 FlyBaseID:FBgn0030551 Length:344 Species:Drosophila melanogaster
Sequence 2:NP_001001979.1 Gene:Megf10 / 70417 MGIID:2685177 Length:1147 Species:Mus musculus


Alignment Length:396 Identity:88/396 - (22%)
Similarity:121/396 - (30%) Gaps:128/396 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 CSSDAQCAQFERGRC--VDMACICTARGSGERVPCTPLEERLKLTNIIGGACPCPMPNAICHTRW 91
            |||..||.  .|..|  :..||.|.|...|.|  |....|:....|.....|.| ...|.|....
Mouse   148 CSSRCQCK--NRALCNPITGACHCAAGYRGWR--CEDRCEQGTYGNDCHQRCQC-QNGATCDHIT 207

  Fly    92 QQCHCSEGHVSSDDRRRCLPAVVPVGGSCEFQQQCQRADRFSSC--IGNQCLCLNQF-------E 147
            .:|.||.|:..:.....|.|.  ..|..||.:..||..   ..|  :..:|.|.:.:       .
Mouse   208 GECRCSPGYTGAFCEDLCPPG--KHGPHCEQRCPCQNG---GVCHHVTGECSCPSGWMGTVCGQP 267

  Fly   148 FHEGRCLSVLQSSCLEDKDC---GSCGASICLTKTKRCGCSKNFVHNHNMTKCIKGS-------- 201
            ..|||    ...:|.::..|   |:|.|:     |.:|.||..:.......:|..||        
Mouse   268 CPEGR----FGKNCSQECQCHNGGTCDAA-----TGQCHCSPGYTGERCQDECPVGSYGVRCAEA 323

  Fly   202 ---AYGDTCEH-SSPCKLNLG-------------------ADGRCLDHL------------CVCR 231
               ..|..|.| |..|....|                   .|.||..||            |.|:
Mouse   324 CRCVNGGKCYHVSGTCLCEAGFSGELCEARLCPEGLYGIKCDKRCPCHLDNTHSCHPMSGECGCK 388

  Fly   232 ------------STHYPKRVANEVAKDEND-DLDAVNNLERITCAP---------IVPFGAL--- 271
                        |..:......::...:|. |.|:|..  |..|||         ..|.|..   
Mouse   389 PGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG--RCACAPGFKGTDCSTPCPLGRYGIN 451

  Fly   272 ------CRNDSECRMQPMDQENATASIGHPMVCN-------WG-----ECSCSKTHRLEDNKCVF 318
                  |:||:.|  .|:|......:..|.:.|:       ||     .|.|     |....|..
Mouse   452 CSSRCGCKNDAVC--SPVDGSCICKAGWHGVDCSIRCPSGTWGFGCNLTCQC-----LNGGACNT 509

  Fly   319 VENSAT 324
            ::.:.|
Mouse   510 LDGTCT 515

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11674NP_572948.1 EB 96..153 CDD:279949 15/65 (23%)
Megf10NP_001001979.1 Necessary for interaction with AP2M1, self-assembly and formation of the irregular, mosaic-like adhesion pattern. /evidence=ECO:0000250|UniProtKB:Q96KG7 1..857 88/396 (22%)
EMI 32..99 CDD:284877
EGF_CA 281..326 CDD:304395 11/49 (22%)
EGF_CA 542..587 CDD:304395
Necessary for formation of large intracellular vacuoles. /evidence=ECO:0000250|UniProtKB:Q96KG7 945..1147
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1093..1147
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D561378at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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