DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and pear1

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_700533.4	Gene:	pear1 / 571812	ZFINID:	ZDB-GENE-091230-1	Length:	1020	Species:	Danio rerio

Alignment Length:	370	Identity:	83/370 - (22%)
Similarity:	110/370 - (29%)	Gaps:	124/370 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LSCSSDAQC-----AQFERGRCVDMACICTARGSGER----VPCTPLEERLKLTNIIGGACPCPM 82
            ::||.|..|     ...|:|:|.     |.|..:|||    .|.....|..|      |.|.| .
Zfish   268 INCSKDCLCHNGGHCDQEKGQCQ-----CDAGYTGERCNEECPVGTYGEDCK------GVCDC-A 320

  Fly    83 PNAICHTRWQQCHCSEGHVSSD-DRRRCLPAVVPVGGSCEFQQQCQRADRFSSCIGNQCLC--LN 144
            ..|.|:.....|.|..|..... |.|.|..||        |...||          ::|||  ||
Zfish   321 NGARCYNIHGGCLCEPGFKGPRCDHRMCPEAV--------FGMHCQ----------HRCLCNPLN 367

  Fly   145 QFEFH--EGRCL----------------SVLQSSCLEDKDCGSCGASICLTKTKRCGCSKNFVHN 191
            ....|  :|.|.                ....:.|||  .|......:|.:.|.:|.|...|...
Zfish   368 TLSCHPLKGECTCQPGWAGLYCNETCAQGYYGNGCLE--PCLCVNGGVCDSVTGQCHCPPGFTGL 430

  Fly   192 HNMTKCIKGSAYGDTCEHSSPCKLNLGADGRCLDHLCVCR--------------STHYPKRVANE 242
            |....|..| .||..|  .|.||.........:|..|:|:              .|..|.  .|.
Zfish   431 HCEKLCEDG-FYGKGC--LSACKCVNSIVCSPVDGACICKEGWRGPDCSIACSEGTWGPG--CNR 490

  Fly   243 VAKDENDDLDAVNNLERITCAP---------------------IVPFGALCRNDSECRMQPMDQE 286
            ..|..|.          .:|.|                     |..||..|:|..:|     ..:
Zfish   491 TCKCTNG----------ASCDPADGSCKCTAGWRGASCDEPCLIGTFGPGCQNQCDC-----VHD 540

  Fly   287 NATASIGHPMVC--NWGECSCSK-----THRLEDNKCVFVENSAT 324
            ....|:....:|  .|....|::     |..::.|:.....||||
Zfish   541 EGCESVTGQCLCLPGWTGVRCTQQCPEGTWGIQCNQTCSCLNSAT 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	17/61 (28%)
pear1	XP_700533.4	EMI	29..96	CDD:284877
pear1	XP_700533.4	Laminin_EGF	411..451	CDD:278482	13/42 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910