DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and stab1

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001182543.1	Gene:	stab1 / 570626	ZFINID:	ZDB-GENE-050208-554	Length:	2553	Species:	Danio rerio

Alignment Length:	320	Identity:	70/320 - (21%)
Similarity:	100/320 - (31%)	Gaps:	113/320 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GRAEDLLELSCSSDAQCAQFERGRCVDMACICTARGSGERVPCTPLEERLKLTNIIGGACPCPMP 83
            |:....|:..||::.||   |.|......|:|.                   ....|.||....|
Zfish  1328 GKCPGTLDNWCSNNGQC---EDGLHGTGKCLCN-------------------EGFHGTACEMCEP 1370

  Fly    84 NAICHTRWQQCHCSEGHVSSDDRRRCLP-------------------AVVPV----GGSCEFQQQ 125
            .........:|||..|        :||.                   :||.|    ||.|:....
Zfish  1371 GRYGKDCKSECHCEHG--------KCLDGLEGNGQCICFKGWKGVKCSVVVVDDACGGVCDVNAN 1427

  Fly   126 CQRADRFSSCIGNQCLCLNQFEFHEGRCLSVLQSSCLEDKDCGSCGASICLTKT----KRCGCSK 186
            |...|   |.....|.|...::.:...|..:  :.|.||.  |.|..:...|||    :.|.|:.
Zfish  1428 CISGD---SGTPPTCSCTAGYKGNGTSCEEI--NPCAEDN--GGCSVNANCTKTAPGERTCTCTT 1485

  Fly   187 NFVHNHNMTKCIKGSAYGDTCEHSSPCKLNLGADGRCLDHLCVCRSTHYPKRVANEVAKDENDDL 251
            |::.:            |..|.....|.:|   :|.| |...:|..|. |.|||
Zfish  1486 NYIGD------------GVICVEMDACLVN---NGGC-DENAICMKTG-PNRVA----------- 1522

  Fly   252 DAVNNLERITCAP-IVPFGALCRNDSECRMQPMDQENATASIGHPMVCNW---GE--CSC 305
                    ..|.| .:..|..|...:.||     ::|...|:.  .||.:   ||  |:|
Zfish  1523 --------CACRPGFISQGHRCLAVNPCR-----KDNGGCSVN--AVCRYLGAGERNCTC 1567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	15/79 (19%)
stab1	NP_001182543.1	EGF_3	227..257	CDD:289699
		Fasciclin	379..475	CDD:295423
		FAS1	455..630	CDD:225214
		Fasciclin	504..630	CDD:280607
		EGF_3	819..847	CDD:289699
		EGF_3	859..889	CDD:289699
		EGF_3	901..932	CDD:289699
		EGF_3	938..974	CDD:289699
		Fasciclin	1002..1103	CDD:280607
		Fasciclin	1125..1242	CDD:295423
		EGF_3	1458..1494	CDD:289699	12/49 (24%)
		EGF_3	1500..1536	CDD:289699	14/59 (24%)
		EGF_3	1542..1578	CDD:289699	10/33 (30%)
		Fasciclin	1611..1711	CDD:280607
		Fasciclin	1734..1864	CDD:280607
		EGF_3	2085..2120	CDD:289699
		EGF_3	2128..2163	CDD:289699
		Link_domain_TSG_6_like	2198..2290	CDD:239592
		Fasciclin	2322..2448	CDD:295423
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900