DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and megf10

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_001922524.2	Gene:	megf10 / 564571	ZFINID:	ZDB-GENE-080506-1	Length:	1120	Species:	Danio rerio

Alignment Length:	397	Identity:	86/397 - (21%)
Similarity:	127/397 - (31%)	Gaps:	141/397 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HRWILLLLAGFLATGRAEDLLELS-----------CSSDAQCAQFERGRCVDMACICTARGSG-- 56
            |.|            |.|||.:.|           |.::|.|..      :...|:|:...:|
Zfish   171 HGW------------RCEDLCDHSTYGNNCQQKCLCQNNATCHH------ITGECVCSPGYTGAF 217

  Fly    57 ---------------ERVPCTPLEERLKLTNIIGGACPCP---------MPNAICHT-RW----- 91
                           ||.||    :...:.:.:.|.|.||         .|   |.| |:
Zfish   218 CEDLCPPGKHGQQCEERCPC----QNGGVCHHVTGECSCPAGWMGMVCGQP---CPTGRFGKNCS 275

  Fly    92 QQCHCSEGHVSSDDRRRCLPAVVPVGGSCEFQQQCQRADRFSSCIGNQCLCLNQFE-FH-EGRCL 154
            |:|.|..|.:.|....:|:.:....|..|  |.|||.......| ...|.|:|..: :| .|.||
Zfish   276 QECQCHNGGICSPSTGQCVCSSGYTGERC--QDQCQVGTYGIGC-SQACRCVNGAQCYHVSGACL 337

  Fly   155 SVLQSSCLEDKDCGSCGASIC------LTKTKRCGCSKNFVHN-HNMT---KCIKG--------- 200
                  |.:.....||...||      |...::|.|:.|...: |.|:   .|..|
Zfish   338 ------CEQGYTGESCEERICPDGQYGLKCDRKCPCNTNNTRSCHPMSGECSCQSGWSGLYCNET 396

  Fly   201 ---SAYGDTCEHSSPCKLNLGADGRCLDHLCVCRSTHYPKRVANEVAKDENDDLDAVNNLERITC 262
               ..||:.|:  ..|:...|||...:...|:|.    |....::.|               |.|
Zfish   397 CAPGFYGEACQ--EVCRCQNGADCHSVSGECICA----PGYKGSDCA---------------IAC 440

  Fly   263 APIVPFGALCRNDSECR----MQPMDQENATASIGHPMVCN-------WG-----ECSCSKTHRL 311
            .| ..:|..|.:...|:    ..|:|...:..:..|.:.|:       ||     .|.|......
Zfish   441 PP-GTYGINCTSLCSCKNGAICSPIDGSCSCQAGWHGVDCSINCPSGTWGLGCNLSCVCGNGGAC 504

  Fly   312 E--DNKC 316
            .  |.||
Zfish   505 NALDGKC 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	16/58 (28%)
megf10	XP_001922524.2	EMI	29..96	CDD:284877
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010