DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and Dkk4

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001102802.1	Gene:	Dkk4 / 502097	RGDID:	1563172	Length:	221	Species:	Rattus norvegicus

Alignment Length:	172	Identity:	37/172 - (21%)
Similarity:	54/172 - (31%)	Gaps:	62/172 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 SSCLEDKDCG---SCGA-----SICLT---KTKRCG----CSKNFVHNHNMTKCIKGS------- 201
            |.|:.||||.   .|.|     |.|.|   ..:||.    |....|..:::...::.:
  Rat    39 SQCVSDKDCNVGKFCFALHDERSFCATCRRVRRRCQRSAMCCPGTVCVNDVCTAVENTRPVMDRN 103

  Fly   202 --------AYGDT---CEHSSP--------CKLNLGADGR-------CLDHLCVCRSTHYPKRVA 240
                    |.|.|   .|.:.|        .:.|.|.:|.       |...||..|  |:..::.
  Rat   104 TDGQDGTYAEGTTKWPAEENRPQGKPSTKKSQSNKGQEGESCLRTSDCGPGLCCAR--HFWTKIC 166

  Fly   241 NEV--------AKDENDDLDAVNNLERITCAPIVPFGALCRN 274
            ..|        .:...|...|....:|..|.|    |..||:
  Rat   167 KPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGP----GLSCRS 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949
Dkk4	NP_001102802.1	Dickkopf_N	41..91	CDD:282549	14/49 (29%)
Dkk4	NP_001102802.1	Prokineticin	<145..202	CDD:148298	12/62 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900