DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and Stab2

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_038934441.1	Gene:	Stab2 / 282580	RGDID:	628822	Length:	2569	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	72/327 - (22%)
Similarity:	106/327 - (32%)	Gaps:	102/327 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LSCSSD--AQCAQFERGRCVDMACICTARGSGERVPCTPLEERLKLTNI-----------IGGAC 78
            :|||:.  ::|....:...:..:|..::|....:..|.      :..|:           .|..|
  Rat   682 VSCSTKHWSKCPADSKPATIFSSCFYSSRVRNLKSGCA------RYCNVTVEIPRCCKGFFGPDC 740

  Fly    79 -PCP----MPNAICHTRWQ---------QCHCSEGHVSSDDRRRCLPAVVPVGGSCEFQQQCQRA 129
             |||    .|   |....|         .|.|.:|.               .|..|:|   |...
  Rat   741 TPCPGGFLTP---CSGNGQCMDGLAGNGTCICQDGF---------------QGSMCQF---CSDP 784

  Fly   130 DRFSSCIGNQCLCL-----NQFEFHEGRCLSVLQSSCLEDKDCGSCGASICLTKTKRCGCSKNFV 189
            :|:.......|||:     |:.: .:|.|||   .:|.|    |:.| ..|..:|..||....|.
  Rat   785 NRYGPRCNRTCLCVHGTCDNRLD-SDGACLS---GTCRE----GTAG-RFCDKQTSACGPYVQFC 840

  Fly   190 HNH------NMT-KCIKGSAY---GDTCEHSSPCKLNLGADGRCLDHL-CVCRSTHYPKRVANEV 243
            |.|      |.| .|:....|   |..|....|| |.|.:.|.|..:. |:..||.....|..:.
  Rat   841 HIHASCEYSNKTASCVCNEGYEGDGVLCSKKDPC-LGLTSRGGCSPNAECIQTSTGTYSCVCQQG 904

  Fly   244 AKDENDDLDAVNNLERITCAPIVPFGALCRNDSECRMQPMDQENATASIGHPMVCNWGECSCSKT 308
            ......|...:||     |  ::|....|.:::.|......|               .||.|.|.
  Rat   905 WTGNGRDCVGINN-----C--LLPSSGGCHDNATCLYVGPGQ---------------NECECKKG 947

  Fly   309 HR 310
            .|
  Rat   948 FR 949

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	12/61 (20%)
Stab2	XP_038934441.1	EGF_CA	254..283	CDD:419698
		EGF_3	334..369	CDD:403986
		Fasciclin	390..512	CDD:396845
		Fasciclin	533..658	CDD:396845
		EGF_3	840..868	CDD:403986	7/27 (26%)
		EGF_3	881..912	CDD:403986	6/30 (20%)
		EGF_3	923..955	CDD:403986	8/42 (19%)
		EGF_3	961..997	CDD:403986
		Fasciclin	1014..1133	CDD:396845
		Fasciclin	1152..1269	CDD:396845
		EGF_3	1478..1514	CDD:403986
		EGF_3	1520..1556	CDD:403986
		EGF_3	1562..1598	CDD:403986
		Fasciclin	1629..1729	CDD:396845
		Fasciclin	1754..1885	CDD:396845
		EGF_CA	2059..2084	CDD:419698
		EGF_3	2090..2125	CDD:403986
		EGF_3	2131..2168	CDD:403986
		Link_Domain	2202..2294	CDD:413401
		FAS1	2360..2449	CDD:214719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900