DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11674 and pqn-25

DIOPT Version :9

Sequence 1:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_741140.1	Gene:	pqn-25 / 175759	WormBaseID:	WBGene00004114	Length:	672	Species:	Caenorhabditis elegans

Alignment Length:	393	Identity:	82/393 - (20%)
Similarity:	134/393 - (34%)	Gaps:	140/393 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LSCSSDAQCAQFERG-RCVDMAC-------ICTARG-SGERVPCTPLEERLKLTNIIGGAC---- 78
            ::||::.|||.   | .|.:.||       .|::.| :|.....|.:..:...:..||.||
Worm   124 VTCSTNTQCAS---GYTCNNGACCPNTNSNTCSSNGNNGCLAGQTMVNGQCYNSVNIGSACQSTQ 185

  Fly    79 ------PCPMPNAICHTRW----QQC------HCSEGHVSSDDRRRCLPAVVPVGGSCEFQQQCQ 127
                  .|......|::.:    |||      :|..|.||.:.  :|:....| |.:|:...||
Worm   186 QCLGGSQCQNNICQCYSGYVNVNQQCVISNGLNCQLGTVSYNS--QCITLASP-GQNCQTSSQC- 246

  Fly   128 RADRFSSCIGNQCLCLNQFEFHEGRC---------------------LSVLQSSCLEDKDCGSCG 171
             .|. |.|:...|.|.|.:....|.|                     ||::..:|:.::.|  .|
Worm   247 -IDN-SVCMNQMCTCNNNYRLVYGYCVPITSSICQQTQTLVNNQCVLLSIVGETCIANQQC--VG 307

  Fly   172 ASICLTKTKRC-----------------GCSKNFVHNHNMTKCIKGSAYGDTCEHSSPCKLNLGA 219
            .::|.:.|.:|                 .|:.|.|..:.|  |......|.:|..|..| ||
Worm   308 GAMCNSGTCQCTNGATAMYGYCISSSSSSCNSNQVSINGM--CYNTVQVGGSCSFSQQC-LN--- 366

  Fly   220 DGRCLDHLCV-------CRSTHYPKRVANEVAKDENDDLDAVNNLERITCAPIVPFGALCRNDSE 277
            :..|.:::||       |.:        |:|         .::|    .|...|..|:.|....:
Worm   367 NAVCTNNICVSTFCSVSCST--------NQV---------CISN----QCYNYVSIGSQCVGSQQ 410

  Fly   278 CRMQPMDQENATASIGHPMVCNWGECSCSK----------THRLEDNKC----VFVENSATNYQL 328
            |    :......:||          |.|.:          .:...:|:|    |.:.|...|...
Worm   411 C----LSNSQCISSI----------CQCPQGTQQSNGVCTGNNNNNNQCQPNQVLINNQCYNTVS 461

  Fly   329 RGF 331
            .||
Worm   462 IGF 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:279949	17/56 (30%)
pqn-25	NP_741140.1	EB	160..211	CDD:279949	8/50 (16%)
		EB	219..270	CDD:279949	17/56 (30%)
		EB	278..329	CDD:279949	8/52 (15%)
		EB	341..>376	CDD:279949	10/40 (25%)
		EB	384..435	CDD:279949	13/85 (15%)
		EB	450..496	CDD:279949	5/15 (33%)
		EB	504..555	CDD:279949
		EB	563..614	CDD:279949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810