Protein Alignment CG11674 and Dkk1

DIOPT Version :10

• Sequence 1: NP_572948.1
• Gene: CG11674 / 32374
• FlyBaseID: FBgn0030551
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_034181.2
• Gene: Dkk1 / 13380
• MGIID: 1329040
• Length: 272
• Species: Mus musculus
• Alignment Length: 220
• Identity: 45/220 - (20%)
• Similarity: 79/220 - (35%)
• Gaps: 66/220 - (30%)

  Fly   137 GNQCLCLNQFEFHEGRCLSVLQSSCLEDKDCGS---C-----------GASICLTKTKRCGCSKN 187
            ||:...|:.::.:          .|.||::|||   |           |..|||...||
Mouse    72 GNKYQTLDNYQPY----------PCAEDEECGSDEYCSSPSRGAAGVGGVQICLACRKR------ 120

  Fly   188 FVHNHNMTKCIKGSAYGDTCEHSSPCKLNLGADGRCL--DHLCVCRSTHYPK-RVANEVAKDEND 249
                  ..:|::         |:..|..|...:|.|:  ||      :|:|: .:...:.::..:
Mouse   121 ------RKRCMR---------HAMCCPGNYCKNGICMPSDH------SHFPRGEIEESIIENLGN 164

  Fly   250 DLDAV--NNLERITCAPIVPF------GALCRNDSECRMQPMDQENATASIGHPMVCNWGECSCS 306
            |.:|.  :...|.|......:      |::|...|:|........:..:.|..|::.....|:..
Mouse   165 DHNAAAGDGYPRRTTLTSKIYHTKGQEGSVCLRSSDCAAGLCCARHFWSKICKPVLKEGQVCTKH 229

  Fly   307 K---THRLE-DNKCVFVENSATNYQ 327
            |   :|.|| ..:|...|..|...|
Mouse   230 KRKGSHGLEIFQRCYCGEGLACRIQ 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11674	NP_572948.1	EB	96..153	CDD:460294	3/15 (20%)
Dkk1	NP_034181.2	Dkk1_N_Cys1	16..142	CDD:438010	21/100 (21%)
		DKK-type Cys-1	86..141		18/75 (24%)
		Dkk1_Cys2	188..270	CDD:437998	15/67 (22%)
		DKK-type Cys-2	195..269		14/60 (23%)