Protein Alignment Prp16 and hrpA

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_415931.4
• Gene: hrpA / 948444
• ECOCYCID: G6732
• Length: 1300
• Species: Escherichia coli
• Alignment Length: 637
• Identity: 235/637 - (36%)
• Similarity: 364/637 - (57%)
• Gaps: 48/637 - (7%)

  Fly   534 LPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIGCTQPRRVAAMSVAKR 598
            |||...:|::|..||::.|:|:.|||||||||||.:...|.|...:|:||.|||||:||.:||.|
E. coli    77 LPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANR 141

  Fly   599 VSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLST 663
            :::|:.|:.|..:||.:||.|..|:.|::|.|||||||.|..:|..|..|..||:||||||||:.
E. coli   142 IAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNI 206

  Fly   664 DVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMF------SKNTC 722
            |.|.|.|:|::.||.|||:|:||||:|..:|:..|.|.|...:.|||:||:|.:      :.:|.
E. coli   207 DFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTE 271

  Fly   723 EDYVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSD 787
            .|.:: |:..|:......:.||:||||.|:.:|..|.:.|.:.     |.....|||:|::|.:.
E. coli   272 RDQLQ-AIFDAVDELSQESHGDILIFMSGEREIRDTADALNKL-----NLRHTEILPLYARLSNS 330

  Fly   788 LQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANA 852
            .|.::||..|.  |:.|:|||:|||||||.||.||||.|..::..|:.|..:..|.|.|||||:|
E. coli   331 EQNRVFQSHSG--RRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASA 393

  Fly   853 NQRSGRAGRTGPGQAYRLYTQRQYKDELLA---LTVPEIQRTNLANTVLLLKSLGVVDLLQFHFM 914
            |||.||.||...|...|||::    |:.|:   .|.|||.|||||:.:|.:.:||:.|:..|.|:
E. coli   394 NQRKGRCGRVSEGICIRLYSE----DDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFV 454

  Fly   915 DPPPQDNILNSLYQLWILGAL---DHTGA--LTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVL 974
            :.|.:.||.:.:..|..|||:   :...|  ||.||||:::.|:||...:|::.|.:.||..|.:
E. coli   455 EAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAM 519

  Fly   975 IIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVY------QQWRQNNYSSTWCNEH 1033
            ||.|.||:.....||..::..:|....:|...|||.|.::|::      |:...:|.....|...
E. coli   520 IITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSNAFRRLCRTD 584

  Fly  1034 FIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIG-------E 1091
            :::...:|:.:::..||:.::.:..:.|.|...::..:...:.:..      |..||       |
E. coli   585 YLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGL------LSHIGMKDADKQE 643

  Fly  1092 YVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWL 1143
            |...|... ..:.|.|.|:  ...|.:|:..||:.|::.:.:.|..:|..|:
E. coli   644 YTGARNAR-FSIFPGSGLF--KKPPKWVMVAELVETSRLWGRIAARIDPEWV 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	235/637 (37%)
hrpA	NP_415931.4	PRK11131	5..1298	CDD:182986	235/637 (37%)