Protein Alignment Prp16 and hrpB

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_414690.4
• Gene: hrpB / 944845
• ECOCYCID: EG12329
• Length: 809
• Species: Escherichia coli
• Alignment Length: 723
• Identity: 199/723 - (27%)
• Similarity: 319/723 - (44%)
• Gaps: 107/723 - (14%)

  Fly   534 LPVFASRQELLNVIRENSVIIIVGETGSGKTTQL-TQYLHEDGYSKRGMIGCTQPRRVAAMSVAK 597
            |||.|...|||..:.....:::...||:||:|.| .|.|...|.:  |.|...:|||:||.:||:
E. coli     4 LPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAHPGIN--GKIILLEPRRLAARNVAQ 66

  Fly   598 RVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLS 662
            |:::.::.:.|:.|||.:|.::|....|.::.:|:|:|.|...|||||.....:|:||.|||||.
E. coli    67 RLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQ 131

  Fly   663 TDVLFGLLREI-VARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCEDYV 726
            .|:...||.:: ...|.||||::.|||:|:.:........|.....||:|||:..:.........
E. coli   132 ADLALALLLDVQQGLRDDLKLLIMSATLDNDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRF 196

  Fly   727 ESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAK 791
            :.||..|....|....|.:|:|:||..:|:...|.|..|:..     .:.:.|:|..|..:.|.|
E. coli   197 DDAVAVATAEMLRQESGSLLLFLPGVGEIQRVQEQLASRIGS-----DVLLCPLYGALSLNDQRK 256

  Fly   792 IFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRS 856
            ....:..|:||.|:||||||||||::||..|:|....::..::||.|:..|....:|||:..||:
E. coli   257 AILPAPQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRA 321

  Fly   857 GRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDN 921
            |||||..||.:..|..:.| .:...|.:.|||.:::|:..::.|...|..|..|..::|.||..|
E. coli   322 GRAGRLEPGISLHLIAKEQ-AERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVN 385

  Fly   922 ILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIF 986
            :|.:...|.:||||:.. .|:..|::||....||....||:.|.....:|....|.::|..|
E. coli   386 LLAAKRLLQMLGALEGE-RLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEP--- 446

  Fly   987 YRPK-GREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQL 1050
              |: |..|.  ||.....:|            .|:|.:                       |||
E. coli   447 --PRMGNSDL--GVAFSRNQP------------AWQQRS-----------------------QQL 472

  Fly  1051 KDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSA------- 1108
                 .:.|:|.....|..::...:..|:..:.||.:|......|..||...|....|
E. coli   473 -----LKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDGRYQLANGMGAMLDANDALSRHEWL 532

  Fly  1109 -----LYGLGTTPD-------YVVYHELIMTAKEYMQCATAVDGYW-----------LAELGPMF 1150
                 |.| ..:||       .|...||:....:.:|.:..|:  |           ..::|.:.
E. coli   533 IAPLLLQG-SASPDARILLALLVDIDELVQRCPQLVQQSDTVE--WDDAQGTLKAWRRLQIGQLT 594

  Fly  1151 FSVKESGRSGREKKKQA---------------AEHLKEMEEQMLKAQHEMEERKQQAAEREEQLA 1200
            ..|:...:...::..||               ....:::..::|.|...:.|....|.:.|..||
E. coli   595 VKVQPLAKPSEDELHQAMLNGIRDKGLSVLNWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLA 659

  Fly  1201 TKQEIATP 1208
            ..:....|
E. coli   660 ALETWLLP 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	187/646 (29%)
hrpB	NP_414690.4	PRK11664	1..809	CDD:236950	199/723 (28%)