DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(1)G0007 and Dqx1

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_291084.1	Gene:	Dqx1 / 93838	MGIID:	2136388	Length:	718	Species:	Mus musculus

Alignment Length:	667	Identity:	206/667 - (30%)
Similarity:	344/667 - (51%)	Gaps:	28/667 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   529 EQRRFLPVFASRQELLNVIREN--SVIIIVGETGSGKTTQLTQYLHEDGYSK---RGMIGCTQPR 588
            ||||.||::|:|...|..:..:  .|:::.|:.||||:||:.|:..|...::   .|.:..|||.
Mouse    37 EQRRALPIWAARFLFLEHLESSPTGVVLVSGDPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPY 101

  Fly   589 RVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRE--SLRDPELDSYSAI 651
            .:||||:|.||:||||..||.::||:|..||||...|::::..|.:.|:|  |.|.|  .::|.:
Mouse   102 PLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGP--GAWSVL 164

  Fly   652 IMDEAHERSLSTDVLFGLLREIVARR--HDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVD 714
            |:|||.|||:::|:|.||||:...|.  .|.:::|.:......||..|:||.|...:|.......
Mouse   165 ILDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVVVTDPALEPKFQAFWGNSPIVRVPREPGGDP 229

  Fly   715 VMFSKNTC-EDYVESAVKQALQVHLTPNE---GDMLIFMPGQEDIEVTCEVLEERLAEID-NAPA 774
            .:..|:|. .|.||:|.:..|:  |...|   ||:|:::|.:|:|.:.||.|...:..:. ..|.
Mouse   230 TLAYKDTVPTDLVEAACQAVLE--LCQQEEAPGDVLVYLPSEEEISLCCESLSGEMGTLAVPGPP 292

  Fly   775 LSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGM 839
            ..:||::......:|. :::.:...:||.||...:|:.|.::..|.:|||||.....||||||..
Mouse   293 PRVLPLHPGCAQAIQT-VYEDTDVSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRA 356

  Fly   840 DALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLG 904
            ::..:.|||:..|..|..||....||...|||::...:.|...|..|::...||::.||||....
Mouse   357 ESQVLRPISKCQAEARLLRAKGFPPGSCLRLYSKSTLELEAPPLPHPKVCEENLSSLVLLLMRKQ 421

  Fly   905 VVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGC 969
            :.:..:.||:|.|..:.::.:|..|..|.||:..|.|:.||..::||||.|...:.|:.:|...|
Mouse   422 IAEPGECHFLDRPAPEALMRALEDLDYLAALNDDGELSDLGVILSEFPLPPELAKALLASCEFNC 486

  Fly   970 SAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHF 1034
            ..|:|.:.:||:....|.||.....|| .:|...:..:.||.:.:.||:.:.|:.....||....
Mouse   487 VDEMLTLAAMLTAAPGFTRPPLSAGEA-ALRRALEHADGDHSSLIQVYEAFVQSGADEAWCQARG 550

  Fly  1035 IHIKAMRKVREVRQQLKDIM--TQQNLSVISCGIDWD--IVRKCICSAYFYQAAR-LKGIGEYVN 1094
            ::.:::.:.|::|.:|.::|  .:..||..:.|.:.:  .::|.:.|.||.:.|| ..|.|.|:.
Mouse   551 LNWESLCQARKLRAELVELMQRIELPLSQPAFGSEQNRRDLQKALLSGYFLKVARDTDGTGNYLL 615

  Fly  1095 LRTGMPCHLHPTSALYGLGT---TPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKES 1156
            |.......|.|..:.....|   .|.:|:||...::....:...:.:....|.||.|.:|.....
Mouse   616 LTHKHVAQLSPYCSYRNRRTPAQPPTWVLYHSFSISKDNCLCIVSEIQPEMLVELAPPYFLSNLP 680

  Fly  1157 GRSGREKKKQAAEHLKE 1173
            ....|:...|..|...|
Mouse   681 PSESRDLLNQLREGTAE 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	74/194 (38%)
		DEXDc	551..689	CDD:238005	58/144 (40%)
		HELICc	722..870	CDD:238034	47/152 (31%)
		HA2	932..1014	CDD:214852	27/81 (33%)
		OB_NTP_bind	1048..1148	CDD:285018	25/107 (23%)
Dqx1	NP_291084.1	HrpA	9..672	CDD:224557	200/640 (31%)
		DEAQ box	167..170		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	690..718		3/8 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820