Protein Alignment l(1)G0007 and PRP16

DIOPT Version :9

• Sequence 1: NP_572947.1
• Gene: l(1)G0007 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_013012.3
• Gene: PRP16 / 853961
• SGDID: S000001794
• Length: 1071
• Species: Saccharomyces cerevisiae
• Alignment Length: 1061
• Identity: 465/1061 - (43%)
• Similarity: 626/1061 - (59%)
• Gaps: 169/1061 - (15%)

  Fly   235 DDEDGEFG---QRKSDWDMPTPRRHGNKSGDWSVRSGGSRRNHGRQDDTVR-PTP-AHRYNQWAH 294
            ||.:.|..   |:|     |.|.|...|..| .:::...|    :...||: |:| :.:..|..|
Yeast   100 DDNEDELDSPVQKK-----PAPTRTLFKRID-KLKAKQLR----QYSPTVKDPSPNSEQQTQNGH 154

  Fly   295 GRKRSGATPWGEDPESLDLWEEEQRRLDREWYNIDEGYDDENNPFGGPNSEYFRKREEQLEQKRT 359
            ...:.      .:|...::.||     |||||:.|   ||..|....|.|
Yeast   155 AETKD------YEPTRSEVVEE-----DREWYDND---DDYGNLVPEPLS--------------- 190

  Fly   360 KRISAQQRQNNRDNELWERNRMLTSGVVTLISVNDDFDEEALERVHLLVHHI------IPPFLDG 418
                          ||.|..::|.      :..|.|.|:.....|.|....:      |||||..
Yeast   191 --------------ELPEEAKLLP------VIRNIDNDDALRNTVQLYPIPLKQRMEWIPPFLSK 235

  Fly   419 RIVFTKQPEPVV------------------PVKDPTSDMALLARKGSALVRNYREQKERRKAQKK 465
            ..:..|.|..::                  |.::|.|:.:..|::||.||...|...|..:..:.
Yeast   236 FALENKVPTSIIIGSISETSSQVSALSMVNPFRNPDSEFSANAKRGSKLVALRRINMEHIQQSRD 300

  Fly   466 HWELSGTKLGNIMGVQRPQDEDDMRFDKEKDKADYRKDQKFADHMRDQDTG----GKSDFSRKKT 526
            :..:..|.:|.::|::..        :|.|||:    :||..|     ||.    .|.|....|
Yeast   301 NTTVLNTAMGEVLGLENN--------NKAKDKS----NQKICD-----DTALFTPSKDDIKHTK- 347

  Fly   527 ISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSK-RG-MIGCTQPRR 589
              ||   ||||..|.:||::||||.|::|:|||||||||||.|||:|:||:. || .|..|||||
Yeast   348 --EQ---LPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGYANDRGKSIVVTQPRR 407

  Fly   590 VAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCT-SERTVIKYMTDGILLRESLRDPELDSYSAIIM 653
            |||:||||||:.||...||::|||:|||||.| ||.|.:|::||||||||:|.|..||.||.:|:
Yeast   408 VAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVTDGILLRETLLDDTLDKYSCVII 472

  Fly   654 DEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFS 718
            ||||||||:||:|.|..:.::|||.|||||:|||||::.||:.||||.|.||||||||||..:::
Yeast   473 DEAHERSLNTDILLGFFKILLARRRDLKLIITSATMNAKKFSAFFGNAPQFTIPGRTFPVQTIYT 537

  Fly   719 KNTCEDYVESAVKQALQVHLTP--NEGDMLIFMPGQEDIEVTCEVLEERL----------AEIDN 771
            .|..:||||:||.||:::||..  :.||:||||.||||||.|.:.|:|:.          |..:.
Yeast   538 SNPVQDYVEAAVSQAVKIHLANDCSSGDILIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEE 602

  Fly   772 APALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPR 836
            ...:.||||||.||:|||.||||......||.::||||||||||:.||.||||.||.|||||||:
Yeast   603 INDIEILPIYSALPADLQFKIFQDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPK 667

  Fly   837 IGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLK 901
            ||:|:|.|.|||:|||:|||||||||.||.||||||:..:|:::...|:||||||||:||:||||
Yeast   668 IGLDSLVITPISKANADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLK 732

  Fly   902 SLGVVD-LLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVAC 965
            ||.|.| |.:|.|:|.||....|:|||:||.:||:|.:|.||.||.|||:|||.|...::|::|.
Yeast   733 SLDVTDELSKFPFIDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKILLIAV 797

  Fly   966 RMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWC 1030
            |.|||.|:|.||||||||.:|||||.|:.|||..|.||...:|||||.|||::|||.||:||.||
Yeast   798 RNGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHLTLLNVFEQWRANNFSSHWC 862

  Fly  1031 NEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNL 1095
            |:||:..|::.:.|::|.||..|:..|.:.|||.|.||||::|||||.:.:|||::.|:..||:|
Yeast   863 NKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDIIKKCICSGFAHQAAKITGLRNYVHL 927

  Fly  1096 RTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKESGRSG 1160
            :||:...|||||||:|||..|.|||||||:||:|||:.|.|:||.:||.|.|.:.:.:|
Yeast   928 KTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDPFWLMEYGGLLYDIK------ 986

  Fly  1161 REKKKQAA----------EH---------------LKEMEEQMLK----AQHEMEERKQQAAERE 1196
            |.|..|.|          ||               .|:|.:.:::    ..:..:|.|:|..:::
Yeast   987 RIKNDQEATTTGLFGEHYEHTLDKVEDDIDINIRRCKDMRDSVIQELKMTDNSNKEDKKQKTKKQ 1051

  Fly  1197 EQLATKQEIATPGNATPRRTP 1217
            ..|..|:....|   ..||.|
Yeast  1052 NILNGKENSMKP---FKRRKP 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	123/188 (65%)
		DEXDc	551..689	CDD:238005	91/140 (65%)
		HELICc	722..870	CDD:238034	92/159 (58%)
		HA2	932..1014	CDD:214852	48/81 (59%)
		OB_NTP_bind	1048..1148	CDD:285018	56/99 (57%)
PRP16	NP_013012.3	HrpA	319..1071	CDD:224557	405/775 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343754
Domainoid	1	1.000	190	1.000	Domainoid score	I639
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8512
Inparanoid	1	1.050	757	1.000	Inparanoid score	I70
Isobase	1	0.950	-	0	Normalized mean entropy	S613
OMA	1	1.010	-	-		QHG52596
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	1	1.000	-	-		oto100033
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	1	1.100	-	-	LDO	PTHR18934
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R986
SonicParanoid	1	1.000	-	-		X141
TreeFam	0	0.000	Not matched by this tool.
	15	14.780