DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(1)G0007 and AT5G10370

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_196599.2	Gene:	AT5G10370 / 830901	AraportID:	AT5G10370	Length:	1775	Species:	Arabidopsis thaliana

Alignment Length:	1006	Identity:	289/1006 - (28%)
Similarity:	462/1006 - (45%)	Gaps:	198/1006 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 SGGSRRNHGRQDDTVRPTPAHRYNQWAHGRKRSGATPWGEDPESLDLWEEEQRRLDREWYNIDEG 331
            |.|.|....|:..:...:..:|||    .|....:.|....|    .|.::..:....  |....
plant     8 SDGGRSATDRRQQSSHSSSTNRYN----SRSAQSSPPLNHRP----TWNQQHSQYPNS--NFPPN 62

  Fly   332 YDDENNPFGGPNSEYFRKREEQLEQKRTKRISAQQRQNNRDNEL-WERNRMLTSGVVTLISVNDD 395
            |..:.||..|.:....|.|...:.|      .......|.|.:| :...:.....:..|..:.:
plant    63 YRRDRNPSSGYSPPVTRARPNFIVQ------LLHPAAANSDTKLCFSTKKQEIESLALLCEIPE- 120

  Fly   396 FDEEALERVHLLVHHIIPPF--------------------------LDGRIVFTKQ--PEPVVP- 431
                  |.:|      :|.|                          |.|:..|..:  |..:||
plant   121 ------ESIH------VPQFGCIAGSFSFRQWVDARSAVVALWDYRLQGKHEFVPELIPNVIVPS 173

  Fly   432 ----VKDPTSD------MALLAR-KGSALVRNYREQK------------------ERRKAQKKHW 467
                :||...|      ::|:.. :|...||...|:|                  |::||.:...
plant   174 DMNELKDRLRDLFSSHILSLMENGEGVKKVRLEIEEKSRQVVSFSSKRGLKFEVFEKKKAIEAER 238

  Fly   468 ELSGTKLGNIMGVQRP-------QD--EDDMRFDKEKDKADYRKDQKFADHMRDQDTGGKSDFSR 523
            :|...:|.......:.       ||  |.|:..::|.|.|.:..:             |..|:.|
plant   239 DLVVNRLEEFNNAMKSILRYLIGQDGYEFDLDDEEEGDVAVFCLE-------------GAYDWRR 290

  Fly   524 KKTI--SEQRRF---LPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIG 583
            ...:  .|.||.   ||::|.|:::|..|....:::::|||||||:|||.|:|.:.|.:....|.
plant   291 IHCLIRRECRRLEDGLPIYAYRRQILKKIHREQIMVLIGETGSGKSTQLVQFLADSGVAASESIV 355

  Fly   584 CTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTV---------------IKYMTDG 633
            |||||::|||::|.||.:|.              ..|..|.||               :.||||.
plant   356 CTQPRKIAAMTLADRVREES--------------SGCYEENTVSCTPTFSSTEEISSKVVYMTDN 406

  Fly   634 ILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFF 698
            .||:..::|..|...|.:|:||||||||:||:|..||:::::||.||:|::.|||.|:.:.:.:|
plant   407 CLLQHYMKDRSLSGISCVIIDEAHERSLNTDLLLALLKKLLSRRIDLRLVIMSATADAKQLSQYF 471

  Fly   699 GNVPTFTIPGRTFPVDVMFSKNTCED---------YVESAVKQALQVHLTPNEGDMLIFMPGQED 754
            .:.....:.||.|||::::|.:..|:         ||...||.|:::|.|..||.:|.|:..|.:
plant   472 FSCGILLVNGRNFPVEIVYSPSDTEENSVVGGIASYVGDVVKMAVEIHKTEKEGTILAFLTSQAE 536

  Fly   755 IEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGI 819
            :|..|    ||..    .|:...||::.:|..:.|.::|| :..|.||.:.||||||||||:.|:
plant   537 VEWAC----ERFI----TPSAIALPLHGKLSFEEQFRVFQ-NHPGRRKVIFATNIAETSLTIPGV 592

  Fly   820 IYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALT 884
            .||||||..|...|.||.||..|::..:||::|.||:||||||.||:.||||::..: |.:....
plant   593 KYVIDSGMVKESKYEPRTGMSILKVCRVSQSSARQRAGRAGRTEPGRCYRLYSKNDF-DSMNLNQ 656

  Fly   885 VPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGA-LDHTGA--LTTLGR 946
            .|||:|.:|...:|.:.:|||.::.:|:|:|.|..:.|..::..|..||| ::..|.  ||..|.
plant   657 EPEIRRVHLGVALLRMLALGVNNIAEFNFVDAPVPEAIAMAVQNLVQLGAVVEKNGVHELTQEGH 721

  Fly   947 QMAEFPLDPPQCQMLIVAC---RMGCSAEVLIIVSMLSVPSIFYRPKGRED--EADGVREKFQRP 1006
            .:.:..|: |:...||:.|   |||....||..| |.:..|||.|....:|  :||.::.:|...
plant   722 CLVKLGLE-PKLGKLILGCFRHRMGKEGIVLAAV-MANASSIFCRVGNFDDKMKADRLKVQFCNQ 784

  Fly  1007 ESDHLTYLNVYQQW------RQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCG 1065
            ..|..|.|:||::|      |:|.    ||.|:.::.|:||:..:..::| :|..::.|:::|..
plant   785 NGDLFTLLSVYKEWASLPRERRNK----WCWENSLNAKSMRRCEDTVKEL-EICIERELTLVSPS 844

  Fly  1066 IDW-----------DIVRKCICSAYFYQAARLKGIGE--YVNLRTGMPCHLHPTSALYGLGTTPD 1117
            . |           ..::..|.::.....|...|..:  |....||....|||:.:|...|..|.
plant   845 Y-WVWNPNEGTKHDKHLKMVILASLAENVAMYTGYNQLGYEVALTGQQVQLHPSCSLLAFGQKPS 908

  Fly  1118 YVVYHELIMTAKEYMQCATAVDGYWLAELGP 1148
            :||:.||:....:|:.|.||.|...|..|.|
plant   909 WVVFGELLSIVDQYLVCVTACDFEALYMLDP 939

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	77/203 (38%)
		DEXDc	551..689	CDD:238005	60/152 (39%)
		HELICc	722..870	CDD:238034	65/156 (42%)
		HA2	932..1014	CDD:214852	29/89 (33%)
		OB_NTP_bind	1048..1148	CDD:285018	28/112 (25%)
AT5G10370	NP_196599.2	DEXDc	305..489	CDD:214692	74/197 (38%)
		DEXDc	323..461	CDD:238005	59/151 (39%)
		SrmB	<408..>647	CDD:223587	103/247 (42%)
		Helicase_C	510..634	CDD:278689	56/132 (42%)
		HA2	703..792	CDD:214852	29/90 (32%)
		OB_NTP_bind	837..940	CDD:285018	27/104 (26%)
		RING	1563..>1591	CDD:238093
		IBR	1628..1696	CDD:214763
		IBR	1697..1751	CDD:279784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810