DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(1)G0007 and AT3G26560

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_189288.1	Gene:	AT3G26560 / 822264	AraportID:	AT3G26560	Length:	1168	Species:	Arabidopsis thaliana

Alignment Length:	1158	Identity:	450/1158 - (38%)
Similarity:	654/1158 - (56%)	Gaps:	176/1158 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 KKPDTKSFEKLRG-QLREHKDDTPSHTGGVSEKARERLREHIQRDRKRGPVSSTAAEGRDRDRDW 162
            ||.:....:|.:| .:::.||........:..:|.||.||                |.|:||||
plant    85 KKKEEGDDQKFKGLAIKDTKDKVKELEKEIEREAEERRRE----------------EDRNRDRD- 132

  Fly   163 DRDRRRDRDRDRDRDRDRRQHRERERDRHRSWDRDRGRDRDRDRSMSERSVHTPREPGTPGGSSG 227
            .|:..|||||||:||||.|      |||||..:|:||.:...||    ||....||.|...|..|
plant   133 RRESGRDRDRDRNRDRDDR------RDRHRDRERNRGDEEGEDR----RSDRRHRERGRGDGGEG 187

  Fly   228 GISNSSWDDEDGEFGQRKSDWDMPTPRRHGNKSGDWSVRSGGSRRNHGRQDDTVRPTPAHRYNQW 292
                     ||....:|..|..:...:...|:...:.|..|          ...|...|..:.|:
plant   188 ---------EDRRRDRRAKDEYVEEDKGGANEPELYQVYKG----------RVTRVMDAGCFVQF 233

  Fly   293 AHGRKRSG-------ATPWGEDPESLDLWEEEQRRLDREWY----------------NIDEGYDD 334
            ...|.:.|       ||      ..:|..:|..:| |.|.|                ::|:....
plant   234 DKFRGKEGLVHVSQMAT------RRVDKAKEFVKR-DMEVYVKVISISSDKYSLSMRDVDQNTGR 291

  Fly   335 ENNPFGGPNSE--------YFRKREEQL------------------EQKRTKRISAQQRQNNRDN 373
            :..|...|:.|        .:|.::.|:                  .::..|::|:.:|
plant   292 DLIPLRKPSDEDDSSRSNPSYRTKDGQVTKTGISGIRIVEENDVAPSRRPLKKMSSPER------ 350

  Fly   374 ELWERNRMLTSGVVTLISVNDDF-------------DEEALERVHLLVHHIIPPFLDGRIVFTKQ 425
              ||..:::.|||:.:    |:|             :|.|.|.:.:.::...|.||.|:..::..
plant   351 --WEAKQLIASGVLRV----DEFPMYDEDGDGMLYQEEGAEEELEIEMNEDEPAFLQGQTRYSVD 409

  Fly   426 PEPVVPVKDPTSDMALLARKGSALVRNYREQKERRKAQKKHWELSGTKLGNIMGVQRPQD----- 485
            ..||...|:|...::..|...|||.:..||.:|:::.         |.|.:|     |:|
plant   410 MSPVKIFKNPEGSLSRAAALQSALTKERREMREQQQR---------TMLDSI-----PKDLNRPW 460

  Fly   486 EDDMRFDKEK--------------DKADYRKDQKFADHMRDQDTGGKSDFSR--KKTISEQRRFL 534
            ||.|....|:              |..:::||.          .|....|.:  |.:|.|||..|
plant   461 EDPMPETGERHLAQELRGVGLSAYDMPEWKKDA----------FGKTPTFGQRSKLSIQEQRESL 515

  Fly   535 PVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIGCTQPRRVAAMSVAKRV 599
            |::..::||:..:.:|.|::::||||||||||:||||.|.||:.:|.||||||||||||||||||
plant   516 PIYKLKKELIQAVHDNQVLVVIGETGSGKTTQVTQYLAEAGYTTKGKIGCTQPRRVAAMSVAKRV 580

  Fly   600 SDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTD 664
            ::|...:|||:|||||||||||...|||||||||:||||.|.|..|..||.|::||||||::.||
plant   581 AEEFGCRLGEEVGYAIRFEDCTGPDTVIKYMTDGMLLREILIDENLSQYSVIMLDEAHERTIHTD 645

  Fly   665 VLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCEDYVESA 729
            ||||||::::.||.||:|||||||:|:.||:.:|.|...||||||||||:::::|....||:::|
plant   646 VLFGLLKKLMKRRLDLRLIVTSATLDAEKFSGYFFNCNIFTIPGRTFPVEILYTKQPETDYLDAA 710

  Fly   730 VKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEERLAEI-DNAPALSILPIYSQLPSDLQAKIF 793
            :...||:|||..|||:|:|:.|||:|:..|:.|.||:..: .|.|.|.|||:||.|||::|::||
plant   711 LITVLQIHLTEPEGDILVFLTGQEEIDSACQSLYERMKGLGKNVPELIILPVYSALPSEMQSRIF 775

  Fly   794 QKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGR 858
            .....|.||.||||||||.|||:|||.||:|.|:.|..||||:.|:::|.|.|||||:|.||:||
plant   776 DPPPPGKRKVVVATNIAEASLTIDGIYYVVDPGFAKQNVYNPKQGLESLVITPISQASAKQRAGR 840

  Fly   859 AGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNIL 923
            |||||||:.|||||:..|::|:...::|||||.||..|.|.:|::|:.|||.|.|||||....::
plant   841 AGRTGPGKCYRLYTESAYRNEMPPTSIPEIQRINLGMTTLTMKAMGINDLLSFDFMDPPQPQALI 905

  Fly   924 NSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYR 988
            :::.||:.|||||..|.||.|||:||||||:||..:||:.:..:|||.|:|.:::|:...:||||
plant   906 SAMEQLYSLGALDEEGLLTKLGRKMAEFPLEPPLSKMLLASVDLGCSDEILTMIAMIQTGNIFYR 970

  Fly   989 PKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDI 1053
            |:.::.:||..|.||.:||.||||.|.||:.|:..|:|..||.|:||..:::|:.::||:||..|
plant   971 PREKQAQADQKRAKFFQPEGDHLTLLAVYEAWKAKNFSGPWCFENFIQSRSLRRAQDVRKQLLSI 1035

  Fly  1054 MTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTTPDY 1118
            |.:..|.|::.|.::..:||.|.:.:|:..||......|..|....|.::||:|||:  ...||:
plant  1036 MDKYKLDVVTAGKNFTKIRKAITAGFFFHGARKDPQEGYRTLVENQPVYIHPSSALF--QRQPDW 1098

  Fly  1119 VVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKESGRSGREKKKQAAEHL 1171
            |:||:|:||.||||:..|.:|..||.||.|.||.|.:..:..:.|:::..|.|
plant  1099 VIYHDLVMTTKEYMREVTVIDPKWLVELAPRFFKVSDPTKMSKRKRQERIEPL 1151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	119/185 (64%)
		DEXDc	551..689	CDD:238005	95/137 (69%)
		HELICc	722..870	CDD:238034	82/148 (55%)
		HA2	932..1014	CDD:214852	43/81 (53%)
		OB_NTP_bind	1048..1148	CDD:285018	39/99 (39%)
AT3G26560	NP_189288.1	GH2-like_DHX8	9..76	CDD:409668
		S1_DHX8_helicase	214..290	CDD:240189	16/92 (17%)
		HrpA	504..1129	CDD:224557	328/626 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720