DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)G0007 and dhx35

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_001072515.1	Gene:	dhx35 / 779970	XenbaseID:	XB-GENE-5868299	Length:	701	Species:	Xenopus tropicalis

Alignment Length:	662	Identity:	281/662 - (42%)
Similarity:	429/662 - (64%)	Gaps:	20/662 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   526 TISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRG-MIGCTQPRR 589
            :|..||:.||||..|..:|.::.....::|:||||.||:||:.|||.|.|::..| ::|.|||||
Frog    44 SIEHQRQKLPVFKLRNHILYLVENYQTVVIIGETGCGKSTQIPQYLTEAGWTAEGRVVGVTQPRR 108

  Fly   590 VAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTS-ERTVIKYMTDGILLRESLRDPELDSYSAIIM 653
            |||:|||.||::|....||.:|||.|||:|||. :.|.||::|||:|:||.:.||.|..||.:::
Frog   109 VAAVSVAGRVAEERGAVLGHEVGYCIRFDDCTDPQATRIKFLTDGMLVREMMSDPLLTRYSVLML 173

  Fly   654 DEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFG----NVPT------FTIPG 708
            ||||||:|.||:..|||:::..:|.||:|:|.|||:|:.||..||.    |.|:      .|:.|
Frog   174 DEAHERTLYTDIAIGLLKKVQKKRGDLRLVVASATLDAEKFKAFFNQNDTNDPSRDTCAILTVEG 238

  Fly   709 RTFPVDVMFSKNTCEDYVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEER---LAEID 770
            ||||||:.::::...||::|.|:..:::|.:..|||:|.|:.|||::|....:|.|:   |:...
Frog   239 RTFPVDIFYTQSPVPDYLKSTVQTVMKIHQSDLEGDILAFLTGQEEVESVVSMLVEQARILSRSG 303

  Fly   771 NAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNP 835
            ....|.:||:|:.||:..|.|:|::.|...||.||||||||.|:|::||.:|||.|:.||:.|:|
Frog   304 MKKHLRVLPMYAGLPTSEQMKVFERVSHSARKVVVATNIAEASITINGISFVIDCGFVKLRAYDP 368

  Fly   836 RIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLL 900
            :..:::|.:.|:|||:||||:||:||...||.|||||:..:. :|...||||:||:|||..:|.|
Frog   369 KRAVESLVVVPVSQASANQRAGRSGRNRSGQCYRLYTEEDFL-KLPPSTVPEMQRSNLAPVILQL 432

  Fly   901 KSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALD-HTGALTTLGRQMAEFPLDPPQCQMLIVA 964
            |:||:.::|:|||:.|||..:::.:|..|:.||.|| |......||.:||||||:|...:||:.:
Frog   433 KALGIDNVLRFHFLSPPPAQSMVQALELLYALGGLDKHCRLTEPLGVRMAEFPLNPMFAKMLLES 497

  Fly   965 CRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTW 1029
            ...|||||:|.|.:|:.:.:||..|..::.:|.....||...|.||||.|||::.:.:.|.||.|
Frog   498 GNFGCSAEILSIAAMMQIQNIFVVPPNQKSQAIREHRKFAVEEGDHLTMLNVFEAFIKFNKSSHW 562

  Fly  1030 CNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVN 1094
            |.:.|::.|.:.:...||:|||.::::..:...|...|.|.:.:||.|.:|..||:|...|.|..
Frog   563 CQQRFLNYKGLMRAVTVREQLKKLLSKFKVPKNSSEGDPDPILRCIVSGFFANAAKLHSTGVYRT 627

  Fly  1095 LRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKESGRS 1159
            :|.|...::||||.||. ...|::|::.|::.|.|.||:..|||:..||.||.|.|:  ::....
Frog   628 VRDGHELYIHPTSVLYA-EKPPNWVLFSEVVQTNKYYMRDVTAVESAWLLELAPHFY--QQGTHL 689

  Fly  1160 GREKKKQAAEHL 1171
            .|..|:...::|
Frog   690 SRTSKRAKIDNL 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	97/197 (49%)
		DEXDc	551..689	CDD:238005	74/139 (53%)
		HELICc	722..870	CDD:238034	65/150 (43%)
		HA2	932..1014	CDD:214852	35/82 (43%)
		OB_NTP_bind	1048..1148	CDD:285018	37/99 (37%)
dhx35	NP_001072515.1	HrpA	7..701	CDD:224557	280/660 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010