Protein Alignment Prp16 and dhx38

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: XP_002937626.2
• Gene: dhx38 / 734019
• XenbaseID: XB-GENE-990308
• Length: 1212
• Species: Xenopus tropicalis
• Alignment Length: 1259
• Identity: 758/1259 - (60%)
• Similarity: 948/1259 - (75%)
• Gaps: 88/1259 - (6%)

  Fly     4 DDESGVHRLEGTAGQETRGGLVIRKPKDAGAGGGGGFK--VPQGSMLGLDKLAAKRRAEKERSER 66
            :|:..:|||||:......|||||:| |.:.:.....||  .|:.|:||||.|||::|.|:|..|:
 Frog     2 EDDLSLHRLEGSDPSLEAGGLVIKK-KKSSSNEQHVFKAPAPRSSLLGLDLLAAQKRKEREEREQ 65

  Fly    67 LISFKDSEFDDTGGGSSTPQANASGASSEFAFKKPDTKSFEKLRG-----QLREHKDDTPSHTGG 126
            ....|.|:              .|....|...:.||..:.:..||     ..|..:.:|||:|||
 Frog    66 QEGEKKSK--------------VSSRDWEERDRSPDRPNDKLSRGSHGDRHYRTPRVETPSYTGG 116

  Fly   127 VSEK--ARERLREHIQRDRKRGPVSSTAAEGRDRDRDWDRDRRRDRDRDRDRDRDRRQHRERERD 189
            |:|:  ||.|.||   |:|:...|.:::.:        ||.||::|.|:|: ||..|...|
 Frog   117 VNEEFLARNRQRE---RERREHGVYASSKD--------DRQRRKERGRERE-DRSCRNRSE---- 165

  Fly   190 RHRSWDRDRGRDRDRDRSMSERSVHTPREPGTPGGSSGGISNSSWDDEDGEFG-QRKSDWDMPTP 253
                  ||.|.:|...||..|...|.||:..||       |.|||:::|..:| .::|.|:.|:|
 Frog   166 ------RDSGSERSGRRSEPESPRHKPRDASTP-------SRSSWEEDDSGYGSSQRSQWESPSP 217

  Fly   254 RRHGNKSGDWSVRS--GGSRR---NHGR-QDDTVRPTPAHRYNQWAHGRKRSGATP--------W 304
             ...|:..:.|.||  ..|||   ..|| .:::..|||:::||:||..|:..|:||        .
 Frog   218 -APSNRDSEKSHRSERESSRRERSERGRYSEESPLPTPSYKYNEWASDRRHLGSTPRLSQGRGKQ 281

  Fly   305 GEDPESLDL--------WEEEQRRLDREWYNIDEGYDDENNPFGGPNSEYFRKREEQLEQKRTKR 361
            ..|.:.::.        ||::||:.||:||.:|||:|:.:|.....:.:|.:|||:||:::.:||
 Frog   282 DSDDDKINFMSEEEQRQWEDDQRQADRDWYMMDEGFDESHNALTSTSEDYVKKREQQLQKQTSKR 346

  Fly   362 ISAQQRQNNRDNELWERNRMLTSGVVTLISVNDDFDEEALERVHLLVHHIIPPFLDGRIVFTKQP 426
            :|||:||.|.|||.||.|||||||||..:.|::||:|:...:||||||:::||||||||||||||
 Frog   347 VSAQRRQINEDNERWETNRMLTSGVVQRLEVDEDFEEDNAAKVHLLVHNLVPPFLDGRIVFTKQP 411

  Fly   427 EPVVPVKDPTSDMALLARKGSALVRNYREQKERRKAQKKHWELSGTKLGNIMGVQRPQDEDDMRF 491
            |||:||:|.|||:|::|||||.|||.:||||||:|||.|||||:|||||:||||::..||.|...
 Frog   412 EPVIPVRDATSDLAIIARKGSQLVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKQVDEPDKPI 476

  Fly   492 DKEKDKADYRKDQKFADHMRDQDTGGKSDFSRKKTISEQRRFLPVFASRQELLNVIRENSVIIIV 556
             .|....||:.:||||||||:: :...|||||||::.|||::||:||.:||||.:||:||::|:|
 Frog   477 -AEDGAVDYKAEQKFADHMRER-SEASSDFSRKKSLMEQRQYLPIFAVQQELLTIIRDNSIVIVV 539

  Fly   557 GETGSGKTTQLTQYLHEDGYSKRGMIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCT 621
            ||||||||||||||||||||:..|||.|||||||||||||||||:||...|||:|||||||||||
 Frog   540 GETGSGKTTQLTQYLHEDGYTDYGMIACTQPRRVAAMSVAKRVSEEMQVSLGEEVGYAIRFEDCT 604

  Fly   622 SERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTS 686
            ||:|:||||||||||||.||:.:||.|||:||||||||||:||||||||||:|.||.||||||||
 Frog   605 SEKTLIKYMTDGILLRECLREADLDHYSAVIMDEAHERSLNTDVLFGLLREVVTRRSDLKLIVTS 669

  Fly   687 ATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCEDYVESAVKQALQVHLTPNEGDMLIFMPG 751
            ||||:.||||||||||.|.|||||||||::|||...|||||:|||||||:||:...||:||||||
 Frog   670 ATMDADKFATFFGNVPIFYIPGRTFPVDILFSKTPQEDYVEAAVKQALQIHLSGAAGDILIFMPG 734

  Fly   752 QEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTV 816
            |||||||.:.:.|||.|:|:||.|::||||||||||||||||||:.||:|||:||||||||||||
 Frog   735 QEDIEVTSDQIVERLEELDSAPPLAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTV 799

  Fly   817 DGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELL 881
            |||::|||||||||||:|||||||||||||||||||||||||||||||||.||||||..||:|||
 Frog   800 DGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCYRLYTQSAYKNELL 864

  Fly   882 ALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGR 946
            ..||||||||||:|.|||||||||.|||.||||||||:||:|||:||||||||||:|||||..||
 Frog   865 HTTVPEIQRTNLSNVVLLLKSLGVQDLLLFHFMDPPPEDNMLNSMYQLWILGALDNTGALTPTGR 929

  Fly   947 QMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHL 1011
            .|.||||||...:||||:|.||||:|:||:|||||||:|||||||||:|:|.|||||..||||||
 Frog   930 LMVEFPLDPALSKMLIVSCDMGCSSEILIVVSMLSVPAIFYRPKGREEESDQVREKFAVPESDHL 994

  Fly  1012 TYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCIC 1076
            |||||:.||:.|||||.|||:||||.||||||||||.||||||..|.:|:.|||.||||||||||
 Frog   995 TYLNVFLQWKNNNYSSGWCNQHFIHAKAMRKVREVRAQLKDIMVSQRMSLSSCGSDWDIVRKCIC 1059

  Fly  1077 SAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGY 1141
            :|||:|||||||||||||:||||||||||||:|:|:|.||||:|||||:||.||||||.|||||.
 Frog  1060 AAYFHQAARLKGIGEYVNVRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGE 1124

  Fly  1142 WLAELGPMFFSVKESGRSGREKKKQAAEHLKEMEEQMLKAQHEMEERKQQAAEREEQLATKQ--E 1204
            |||||||||:|:|.:|::.:|.:::|.|.:..|||:|:.|:.::..|::: .|::..|::.:  :
 Frog  1125 WLAELGPMFYSIKHAGKTRQENRRRAKEEVSAMEEEMMLAEEQLRARREE-QEKKNILSSARSLK 1188

  Fly  1205 IATPGN------ATPRRTPARIGL 1222
            |.|||.      .||||||||.||
 Frog  1189 IYTPGRKDQVEPGTPRRTPARFGL 1212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	489/613 (80%)
dhx38	XP_002937626.2	HrpA	517..>1175	CDD:441249	505/658 (77%)