DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)G0007 and dhx40

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_001184155.2	Gene:	dhx40 / 733877	XenbaseID:	XB-GENE-995801	Length:	744	Species:	Xenopus tropicalis

Alignment Length:	739	Identity:	290/739 - (39%)
Similarity:	438/739 - (59%)	Gaps:	59/739 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 KSDFSRKKTISEQ--RRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRG 580
            ||..|.|:..||.  ...||:...:.||:....:|..:|::|:|||||||||.|||::.|:.|.|
Frog     3 KSVRSHKREDSESFYNPILPIHRWKGELVKAATDNPFLIVMGDTGSGKTTQLPQYLYKAGFGKNG 67

  Fly   581 MIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPEL 645
            |||.|||||||.:|||:||::||:..||..|||.:||:|||||||||||||||.|||.:|.||:|
Frog    68 MIGVTQPRRVATISVAQRVAEEMNCSLGSTVGYQVRFDDCTSERTVIKYMTDGCLLRNTLADPDL 132

  Fly   646 DSYSAIIMDEAHERSLSTDVLFGL------LREIVARRHDLKLIVTSATMDSSKFATFFGNVPTF 704
            ..||.|::|||||||||||:||||      ||....|::.||:||.|||::|.|.::||||.|..
Frog   133 TKYSTIVLDEAHERSLSTDILFGLLKKQFQLRSFKRRKYPLKVIVMSATLESQKLSSFFGNCPVV 197

  Fly   705 TIPGRTFPVDVMF-------SKNTCEDYVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVL 762
            ||||:.||:...|       .|::.. ||...||..||.||...|||:|:|:.||.:||..|.:|
Frog   198 TIPGKVFPIKERFLNLIGPRDKDSTA-YVTETVKITLQTHLNEPEGDILVFLTGQAEIERACNLL 261

  Fly   763 EERLAEID--------NAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGI 819
            .::...||        :...|.|||:|..:|:|.|.:||.....|:||||::||||.||:|::||
Frog   262 FKKAEGIDYRHDVYDRSVEGLLILPLYGSMPTDQQKRIFVPPPSGIRKCVLSTNIAATSVTIEGI 326

  Fly   820 IYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALT 884
            .||||||:.|...||||.|:|.|:|.|||::.|.||:||||||.||:.:|:|::..:...:....
Frog   327 RYVIDSGFVKQLNYNPRAGLDILEIVPISKSEAVQRAGRAGRTAPGKCFRIYSEEFWDKCMPDHM 391

  Fly   885 VPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMA 949
            :|:|:||:||:.:|.||.|.:.|:::|.::|.|.:.:||.:|.:|:...|:|.||.:|.||..:.
Frog   392 IPDIKRTSLASVILTLKCLDIHDVIRFPYLDQPEERHILEALKKLYQCSAIDRTGCVTKLGHFII 456

  Fly   950 EFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYR--PKGREDEADGVREKFQRPE---SD 1009
            ||||.|.....:|.|...||...:|.:.:||||..:|.:  ...::.||....|:..:..   :|
Frog   457 EFPLSPNLACAVIKATSFGCEDLLLPVAAMLSVEHVFIQSGQSQKQKEAGLGHEELSQLAGGCND 521

  Fly  1010 HLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMT--QQNLSVISCGIDW---D 1069
            ..|.|.:::|.:.:...::||:|:.||.:|::....|.:|||:|..  :||........|.   :
Frog   522 FATLLYIFEQCKASPKPASWCHENGIHWRALKSALNVEKQLKEITNRLKQNKDFPVEKFDGPRNE 586

  Fly  1070 IVRKCICSAYFYQAARLKGIGEYVNLRT-------GMPCHLHPTSALYGLGTTPDYVVYHELIMT 1127
            ::|:|:|:.||...|| :.:|     ||       |...|:||:|||:|..:..:::::|.:::|
Frog   587 MLRRCLCAGYFSNVAR-RSVG-----RTFCTMDGHGSMIHIHPSSALFGKESELEWILFHNVLVT 645

  Fly  1128 AKEYMQCATAVDGYWLAELGPMFFSVK--ESGRSGRE----------KKKQAAEHLKEMEEQMLK 1180
            :|.:::....:...|:.:|.|....:.  |.....||          :.|...:|..:..|:.|.
Frog   646 SKIFVRTVCPIRYEWVKDLLPKLHDIDAYELSNVAREEVTAEEIIKWESKGETKHCNDGIEEALN 710

  Fly  1181 AQHEMEERKQQAAEREEQLATKQE 1204
            ...:..:.|..:..|...|..||:
Frog   711 KIKKRNDDKSISDARARYLQRKQQ 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	110/193 (57%)
		DEXDc	551..689	CDD:238005	90/143 (63%)
		HELICc	722..870	CDD:238034	74/155 (48%)
		HA2	932..1014	CDD:214852	27/86 (31%)
		OB_NTP_bind	1048..1148	CDD:285018	30/111 (27%)
dhx40	NP_001184155.2	HrpA	1..700	CDD:224557	282/703 (40%)
		DEXDc	40..182	CDD:238005	90/141 (64%)
		HELICc	281..368	CDD:197757	48/86 (56%)
		HA2	441..526	CDD:214852	27/84 (32%)
		OB_NTP_bind	560..668	CDD:285018	31/113 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113216at33208
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010