DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)G0007 and Dhx34

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_001258381.1	Gene:	Dhx34 / 684903	RGDID:	1584452	Length:	1143	Species:	Rattus norvegicus

Alignment Length:	558	Identity:	204/558 - (36%)
Similarity:	307/558 - (55%)	Gaps:	23/558 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 KSDFSRKKTISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMI 582
            |..|.|...:..:|..||:......:|..::|:.|:::.|:||.||:||:.|||...|:|.   :
  Rat   147 KQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH---V 208

  Fly   583 GCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDS 647
            .||||||:|.:|:||||..|..:|.|..|||.||||...|..|.|.::|.|:|||:...:|.|..
  Rat   209 ACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQCEPRLPQ 273

  Fly   648 YSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFP 712
            |..:|:||.|||.|..|.|.|:|:.::.:|.|||:|:.|||::.|.|:::|.:.|...:|||.||
  Rat   274 YQVLIVDEVHERHLHNDFLLGVLQRLLPQRPDLKVILMSATINISLFSSYFSHAPVVQVPGRLFP 338

  Fly   713 VDVMFSKNTCEDYVESAVK----------QALQVHLTPNE-GDMLIFMPGQEDIEVTCEVLEERL 766
            :.|::.....|.....:.|          :|:.....|.| ||:|:|:.|..:|..   ||:...
  Rat   339 ITVVYQPQEAEQSASKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVFLSGMAEIST---VLDAAQ 400

  Fly   767 AEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLK 831
            |.........:||::|.|....|.|:|..:..|:|||:::|||||||:|:|||.:|:|||..|..
  Rat   401 AYATLTQRWVVLPLHSALSVADQDKVFDVAPAGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEM 465

  Fly   832 VYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANT 896
            .|:|:..:..||.:.||||:|.||.|||||||||..||||.:..| |......||||:|..|...
  Rat   466 SYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCYRLYAESDY-DAFAPYPVPEIRRVALDAL 529

  Fly   897 VLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQML 961
            ||.:||:.|.|...|.|::|||..::..::..|...||||.:.|||.:|..:|:.|:|....:|:
  Rat   530 VLQMKSMSVGDPRTFPFIEPPPAASVETAILYLQDQGALDSSEALTPIGSLLAQLPVDVVIGKMM 594

  Fly   962 IVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQ---- 1022
            |:......:..||.|.:.|||.|.|.|......:....|...:..:.|..|..||:..|.|
  Rat   595 ILGSMFSLAEPVLTIAAALSVQSPFTRSAQSNLDCATARRPLESDQGDPFTLFNVFNAWVQVKSE 659

  Fly  1023 -NNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNL 1059
             :..|..||....:....:.::..:|:|.|:::....|
  Rat   660 RSGNSRKWCRRRGVEEHRLYEMANLRRQFKELLEDHGL 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	79/185 (43%)
		DEXDc	551..689	CDD:238005	64/137 (47%)
		HELICc	722..870	CDD:238034	62/158 (39%)
		HA2	932..1014	CDD:214852	25/81 (31%)
		OB_NTP_bind	1048..1148	CDD:285018	3/12 (25%)
Dhx34	NP_001258381.1	HrpA	155..>687	CDD:224557	198/538 (37%)
Dhx34	NP_001258381.1	OB_NTP_bind	798..909	CDD:400182
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810