DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(1)G0007 and Dqx1

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	XP_038964267.1	Gene:	Dqx1 / 680434	RGDID:	1591766	Length:	780	Species:	Rattus norvegicus

Alignment Length:	742	Identity:	223/742 - (30%)
Similarity:	373/742 - (50%)	Gaps:	70/742 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   529 EQRRFLPVFASRQELLNVIREN--SVIIIVGETGSGKTTQLTQYLHEDGYSK---RGMIGCTQPR 588
            ||||.||::|:|...|..:..:  .|:::.||.||||:||:.|:..|...::   .|.:..|||.
  Rat    37 EQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPY 101

  Fly   589 RVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRE--SLRDPELDSYSAI 651
            .:||||:|.||:||||..||.::||:|..||||...|::::..|.:.|:|  |.|.|  .::|.:
  Rat   102 PLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGP--GAWSVL 164

  Fly   652 IMDEAHERSLSTDVLFGLLREIVARR--HDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVD 714
            ::|||.|||:::|:|.||||:...|.  .|.::::.:.:....||..|:||.||..:|.......
  Rat   165 VLDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVIVTDSALEPKFQAFWGNSPTVHVPREPGENP 229

  Fly   715 VMFSKNTC-EDYVESAVKQALQVHLTPNE---GDMLIFMPGQEDIEVTCEVLEERLAEID-NAPA 774
            .:..|:|. .|.||:|.:..|:  |...|   ||:|:::|.:|:|.:.||.|...:..:. ..|.
  Rat   230 TLTYKDTVPADLVEAACQAVLE--LCQREEAPGDVLVYLPSEEEISLCCESLSREMGMLAVPGPL 292

  Fly   775 LSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGM 839
            ..:||::......:|. :::.:...:||.||...:|:.|.::..|.:|||||.....||||||..
  Rat   293 PRVLPLHPGCGQAIQT-VYEDTDVSVRKIVVTHWLADFSFSLPFIQHVIDSGLELRSVYNPRIRA 356

  Fly   840 DALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLG 904
            ::..:..||:..|..|..||....||...|||::.....|...|..|::...||::.|||||...
  Rat   357 ESQVLRRISKCQAEARLLRARGFPPGTCLRLYSKSTLDLEAPPLPHPKVCEENLSSLVLLLKRKQ 421

  Fly   905 VVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGC 969
            :.:..:.||:|.|..:.::.:|..|..|.|||..|.|:.||..::||||.|...:.|:.:|...|
  Rat   422 IAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLPPELAKALLASCEFNC 486

  Fly   970 SAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHF 1034
            ..|:|.:.:||:....|.||.....|| .:|...:..:.||.:.:.||:.:.|:....|||....
  Rat   487 VDEMLTLAAMLTAAPGFTRPPLCAGEA-ALRRGLEHADGDHSSLIQVYEAFVQSGADETWCQARG 550

  Fly  1035 IHIKAMRKVREVRQQLKDIM--TQQNLSVISCGIDWD--IVRKCICSAYFYQAARLKGIGEYV-- 1093
            :..:|:.:.|::|.:|.::|  .:..||:.:.|.:.:  .::|.:.|.||.:|...:|:...:
  Rat   551 LSWEALCQARKLRAELLELMQRIELPLSLPAFGSEQNRRDLQKALLSGYFLKAMMRRGLMSKLPS 615

  Fly  1094 -NLRT-GMP--CHLHPTSALY-GLGTTP--DYVVYHELIMTAKEYM---QCATAVDG---YWL-- 1143
             :|.| |.|  ..|.|.||.. |:..||  .:.::...:::...|:   :.|...||   |.|
  Rat   616 DSLSTSGWPQTAPLAPYSATQAGITATPALAFFIFCASLLSPPMYLCFNEVARDTDGTGNYLLLT 680

  Fly  1144 ----AELGPMFFSVKESGRSGREKKKQAAEH------------LKEMEEQML-----------KA 1181
                |:|.|  :.|..:.|:..:.......|            :.|::.:||           ..
  Rat   681 HKHVAQLSP--YCVYRNRRTPAQPPTWVLYHRFSISKDNCLCTVSEIQPEMLVELAPPYFLSNLP 743

  Fly  1182 QHEMEERKQQAAEREEQLATKQEIATP 1208
            ..|..:...|..|..|..|...|.|:|
  Rat   744 PSESRDLLNQLREGTEPSAAVTETASP 770

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	74/194 (38%)
		DEXDc	551..689	CDD:238005	57/144 (40%)
		HELICc	722..870	CDD:238034	46/152 (30%)
		HA2	932..1014	CDD:214852	28/81 (35%)
		OB_NTP_bind	1048..1148	CDD:285018	30/124 (24%)
Dqx1	XP_038964267.1	HrpA	15..>601	CDD:224557	186/569 (33%)
Dqx1	XP_038964267.1	OB_NTP_bind	662..737	CDD:400182	14/76 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820