Protein Alignment Prp16 and Dhx35

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001402786.1
• Gene: Dhx35 / 362260
• RGDID: 1311165
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 658
• Identity: 291/658 - (44%)
• Similarity: 423/658 - (64%)
• Gaps: 21/658 - (3%)

  Fly   526 TISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRG-MIGCTQPRR 589
            :|.:||:.||||..|..:|.::.....::||||||.||:||:.|||.|.|::..| ::|.|||||
  Rat    46 SIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQVPQYLAEAGWTAEGRVVGVTQPRR 110

  Fly   590 VAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSE-RTVIKYMTDGILLRESLRDPELDSYSAIIM 653
            |||::||.||:||....||.:|||.|||:|||.. .|.||::|||:|:||.:.||.|..||.:::
  Rat   111 VAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVVML 175

  Fly   654 DEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPT----------FTIPG 708
            ||||||:|.||:..|||::|..:|.||:|||.|||:|:.||..||....|          .|:.|
  Rat   176 DEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVILTVEG 240

  Fly   709 RTFPVDVMFSKNTCEDYVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEER---LAEID 770
            ||||||:.:.::...||:::.|...:::|.|..:||:|.|:.|||::|....:|.|:   ||...
  Rat   241 RTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTG 305

  Fly   771 NAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNP 835
            ....|.:||:|:.|||..|.|:|::.|..:||.:||||:||||:|:.||:||||.|:.||:.|||
  Rat   306 MKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNP 370

  Fly   836 RIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLL 900
            |..::.|.:.|:|||:||||:||.||...|:.|||||:..: ::|...||||:||:|||..||.|
  Rat   371 RTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEEAF-EQLPQSTVPEMQRSNLAPVVLQL 434

  Fly   901 KSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALT-TLGRQMAEFPLDPPQCQMLIVA 964
            |:||:..:|:||||.|||..:::.:|..|:.||.||....|| .||.::|||||:|...:||:.:
  Rat   435 KALGIDSVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLES 499

  Fly   965 CRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTW 1029
            ...|||.|:|.|.:|:.:.::|..|..::.:|..|..||...|.||||.||||:.:.::|.||.|
  Rat   500 GNFGCSQEILSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQW 564

  Fly  1030 CNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVN 1094
            |.|||::.|.:.:...||.|||.::.:..:..:|...|.|.|.:||.|.:|..|||....|.|..
  Rat   565 CQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSTGAYRT 629

  Fly  1095 LRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKESGRS 1159
            :|.....|:||.|.||. ...|.:|:|:|:|.|:|.||:..||::..||.||.|.|:   :.|..
  Rat   630 IRDDHELHIHPASVLYA-EKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFY---QQGTH 690

  Fly  1160 GREKKKQA 1167
            ...|.|:|
  Rat   691 LSLKAKRA 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	282/629 (45%)
Dhx35	NP_001402786.1	HrpA	54..>701	CDD:441249	288/650 (44%)