Protein Alignment l(1)G0007 and mle

DIOPT Version :9

• Sequence 1: NP_572947.1
• Gene: l(1)G0007 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Alignment Length: 1096
• Identity: 276/1096 - (25%)
• Similarity: 456/1096 - (41%)
• Gaps: 295/1096 - (26%)

  Fly   224 GSSG----GISNSSWDDEDGEFGQRKSDWDMPTPRRHGNKS----------GDWSVRSGGSRRNH 274
            |.||    |.:....:.:.|:.|.|.|..|....:|..|::          |:|::.:...|.|.
  Fly   112 GQSGPQDLGEAYRPLNHDGGDGGNRYSVIDRIQEQRDMNEAEAFDVNAAIHGNWTIENAKERLNI 176

  Fly   275 GRQDDTVRPTPAHRYNQWAHGRKRSGATPWGEDPE-------SLDLWEEEQRR------------ 320
            .:|.:.:|..  ::|            ||.|  ||       .|.::.....|
  Fly   177 YKQTNNIRDD--YKY------------TPVG--PEHARSFLAELSIYVPALNRTVTARESGSNKK 225

  Fly   321 ---------LDREWY--NIDEGYDDENNPFGGPNSEYFRKREEQLEQKRTKRISAQQRQNNRDNE 374
                     |.|:.:  |:.|       ||.|...   :|::|||:....|
  Fly   226 SASKSCALSLVRQLFHLNVIE-------PFSGTLK---KKKDEQLKPYPVK-------------- 266

  Fly   375 LWERNRMLTSGVVTLISVNDDFDEEALERVHLLVHHIIPPFLDGRIVFTKQPEPVVPVKDPTSDM 439
                   |:..::..|       :|.::.:.|       |.::.|.:..:...|.:|:      :
  Fly   267 -------LSPNLINKI-------DEVIKGLDL-------PVVNPRNIKIELDGPPIPL------I 304

  Fly   440 ALLARKGSALVRNYREQKERRKAQKK----------HW-----------ELSGTKLGNIMGVQRP 483
            ..|:|..|:       |::..|.|:.          :|           ||:.|.:
  Fly   305 VNLSRIDSS-------QQDGEKRQESSVIPWAPPQANWNTWHACNIDEGELATTSI--------- 353

  Fly   484 QDEDDMRFDKEKDKADYRK-DQKFADHMRDQDTGGKSDFSRKKTISEQRRFLPVFASRQELLNVI 547
               ||:..|.|:...|.|: |.::...:                  |.|..||:.|.|.|:|..|
  Fly   354 ---DDLSMDYERSLRDRRQNDNEYRQFL------------------EFREKLPIAAMRSEILTAI 397

  Fly   548 RENSVIIIVGETGSGKTTQLTQYLHED-------GYSKRGMIGCTQPRRVAAMSVAKRVSDEMDT 605
            .:|.|:||.|.||.|||||:.||:.:|       ||:.   |..|||||::|:|||:||:.|...
  Fly   398 NDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYAN---IYVTQPRRISAISVAERVARERCE 459

  Fly   606 QLGEDVGYAIRFEDC-TSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGL 669
            |||:.|||::|||.. ......|.:.|.|:|||:  .:..|...|.||:||.|||.:::|.|..:
  Fly   460 QLGDTVGYSVRFESVFPRPYGAILFCTVGVLLRK--LEAGLRGVSHIIVDEIHERDVNSDFLLVI 522

  Fly   670 LREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCE--DYVESA--- 729
            ||::|....||.:|:.|||:|::||:.:||..|...:|||.|||...|.::..:  |:|.||
  Fly   523 LRDMVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESR 587

  Fly   730 ---------------------------------------------------VKQALQVHLTPNE- 742
                                                               :.:||.:|:....
  Fly   588 RKRKEVEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNI 652

  Fly   743 -GDMLIFMPGQEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVA 806
             |.:|:|:||...|....:.|:......|.: ...|||.:||:|.|.|.|:|:...:|:.|.:::
  Fly   653 PGAILVFLPGWNLIFALMKFLQNTNIFGDTS-QYQILPCHSQIPRDEQRKVFEPVPEGVTKIILS 716

  Fly   807 TNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLY 871
            |||||||:|:|.|::|||....::|::.....:.:......|:.|..||.|||||..||..:.|.
  Fly   717 TNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLC 781

  Fly   872 TQRQY---KDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQFHF----MDPPPQDNILNSLYQL 929
            ::.::   :|.|    .||:.||.|....|.:|.|.:..:  .||    ::|||.|.::.:...|
  Fly   782 SRARFQALEDNL----TPEMFRTPLHEMALTIKLLRLGSI--HHFLSKALEPPPVDAVIEAEVLL 840

  Fly   930 WILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPS-IFYRPKGRE 993
            ..:..||....||.|||.:|..|::|...:|:::....||:..:.|:.|..|..| :|....|:.
  Fly   841 REMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQR 905

  Fly   994 DEADGVREKFQRPESDHLTYLNVYQQWRQ-----NNYSSTWCNEHFIHIKAMRKVREVRQQLKDI 1053
            ..|:..:.......|||:..:...|.||:     .:..:.:|:...:.:..|..:.:.:|||.|:
  Fly   906 RLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDL 970

  Fly  1054 MTQQNL---SVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTT 1115
            :.|...   .:||..:|                .|:.|....:::...:.|          ||..
  Fly   971 LQQAGFPEECMISHEVD----------------ERIDGDDPVLDVSLALLC----------LGLY 1009

  Fly  1116 PDYVVYHE----LIMTAKEYMQCATAVDGYWLAELGPM-FFSVKESGRSGREKKKQ 1166
            |:..|:.|    |...:|..:...|:|:...||...|. ||...|..|:.....||
  Fly  1010 PNICVHKEKRKVLTTESKAALLHKTSVNCSNLAVTFPYPFFVFGEKIRTRAVSCKQ 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	86/193 (45%)
		DEXDc	551..689	CDD:238005	63/145 (43%)
		HELICc	722..870	CDD:238034	52/205 (25%)
		HA2	932..1014	CDD:214852	23/82 (28%)
		OB_NTP_bind	1048..1148	CDD:285018	22/106 (21%)
mle	NP_476641.1	DSRM	4..68	CDD:214634
		DSRM	170..240	CDD:214634	14/85 (16%)
		DEXDc	393..569	CDD:214692	79/180 (44%)
		DEXDc	402..542	CDD:238005	63/144 (44%)
		ATP-synt_B	<584..644	CDD:304375	2/59 (3%)
		Helicase_C	643..772	CDD:278689	44/129 (34%)
		HA2	842..926	CDD:214852	23/83 (28%)
		OB_NTP_bind	974..1078	CDD:285018	24/118 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468112
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18934
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840